Chemical Information from GCMS Analysis of Acetone Extract of Piper guineense Leaves. Part 1
Keywords:
: Piper guineense leaves, Chemical constituents, phytochemicals, GCMS, phytochemical screeningAbstract
Communication in Physical Sciences 2020, 5(4): 437-445
Received 25 June 2020/Accepted 29 July 2020
Applications of plant leaves for various purposes is based on its chemical constituents which may include proximate, elemental, phytochemical, toxicant, amino acid and other toxicants. Knowledge of phytochemical constituents is significant for their pharmaceutical/medicinal values. This study was carried out to investigate the chemical constituents of acetone extract of Piper guineense leaves through phytochemical screening and GCMS analysis. Results obtained from phytochemical screening indicated the major constituents (those whose concentrations were greater than 1%) to include ,6-dimethyloxazolo(5,4-c)pyridazin-4-amine (31.80 %), 3-(1-methylethyl)-cyclohexene (20.99 %), 4-methoxy-N-(4-nitrobenzyl)-benzamide (12.82 %), alpha bisabolene (7.33%), 1,2,3,4,4a,5,6,8a-octahydro-7-methyl-4-methylene-1-(1-methylethyl)-napthalene (4.42 %), 3,7-diacetamidophenoxathin (4.10 %), 1,3,3-trimethyl tricyclo{2,2,1]heptane (2.98%), 3H-indazol-3-one (2.11%), 1H-indene,octahydro-1,7a-dimethyl-4-(1-methylethenyl)-1,4-methano-1H-indene (1.98%), piperidine (1.97%),2,4-disopropenyl-1-methyl-1-vinyl (1.70%), n-hexadecanoic acid (1.68%), eudesdma-4[14],11-diene (1.27%). The pharmaceutical values of the identified constituents were also analsed. The study reveals that acetone extract of Piper guneense contains constituents that are not visible with some other solvents
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References
Boligon AA, Schwanz TG, de Brum TF, Frohlich JK, Nunes L, et al. (2012) Chemical Composition, anti-oxidant and anti-microbial activities of the eessential oil of Scutia buxi-folia reissek leaves. Pharmaceutical Analyti-ca Acta, 3, 199, doi:10.4172/2153-2435.1000199
Chinwendu, S., Ejike, E. N., Ejike, B. U., Oti, W. I. & Nwachukwu, I. (2016). Phytochemi-cal properties of uziza Leave (Piper guin-eesnse). European Journal of Pure and Ap-plied Chemistry, 3, 2, pp. 12-15.
Clarke, S. (2008). Essential Chemistry for aro-maticity, 2nd Edition, Elsevier Ltd. Churchill, Livinstone, https://doi.org/10.1016/B978-0-443-10403-9.X0001-5 Proximate, mineral and phytochemical com-position of Piper guineense seeds and leaves. Journal of Biological Sciences, 18, pp. 329-337.
Limberger, M.E.G. Sobral, J.A.S. Zuanazzi, P.R.H. Moreno, E.E.S. Schapoval & A.T. Henriques (2001) Biological Activities and Essential Oil Composition of Leaves of Ble-pharocalyx salicifolius, Pharmaceutical Bi-ology, 39:4, 308-311, DOI: 10.1076/ phbi.39.4.308.5915
Mohammed, G. J., Omran, A. M., & Hussein, H. M. (2016). Antibacterial and Phytochemical Analysis of Piper nigrum using Gas Chroma-tography – Mass Spectrum and Fourier-Transform Infrared Spectroscopy. Interna-tional Journal of Pharmacognosy and Phy-tochemical Research, 8, 6, pp. 977-996
Naidoo, N., Thangaraj, K., Odhav, B., & Baijnath, H. (2009). Chemical composition and biological activity of the essential oil from cymbopogon nardus (l.) rendle. African Journal of Traditional, Complementary and Alternative Medicines, 6, 395. Retrieved from https://journals.athmsi.org/index.php/ajtcam/article/view/779
Ojinnaka, M. C, Ubbor, S. C., Okudu, H. O. & Uga, U. (2016). Volatile compound analysis of the leaves and seeds of Piper guineense using gas chromatography-mass spectrometry (GC-MS). African Journal of Food Science, 10, 11, pp. 327-332
Olonisakin, A., Oladimeji, M. O. & Lajide, L.(2006). Chemical Composition and Anti-bacterial Activity of Steam Distilled Oil of Ashanti Pepper (Piper guineense) Fruits (Ber-ries). Electronic Journal of Environmental, Agricultural and Food Chemistry, 5, 5, pp. 1531-1535.
Owolabi, M. S., Lawal, O. A.., Ogunwande, I. A., Hauser, R. M. & Setzer, W. N. (2013). Aroma chemical composition of Piper guin-eense Schumach. & Thonn. From Lagos, Ni-geria: a new chemotype. American Journal of Essential oil and Natural Products, 1,1, pp. 7-40.
Oyinloye, B. E., Osunsanmi, F. O., Ajiboye, B. O., Ojo, O. A., & Kappo, A. P. (2017). Mod-ulatory Effect of Methanol Extract of Piper guineense in CCl₄-Induced Hepatotoxicity in Male Rats. International Jjournal of Envi-ronmental Research and Public Health, 14, 9, pp. 955, https://doi.org/10.3390/ijerph14090955
Silva, D. R., Endo, E., Dias Filho, B. P., Apari-cio, D., Cortez, G., Nakaruma, C. V., Svi-dzinski, T. I. A., Souza, A., Young, M. C. M., Tania, U. & Cortez, D. A. G. (2009). Chemi-cal Composition and Antimicrobial Properties of Piper ovatum Vahl. Plant Medica, 70, 9, pp. 1171-1182.
Sun, Z., Chen, B., Zhang, B. & Hu, C. (2005). Four new eudesmanes from Caragana inter-media and their biological activities. Journal of Natural Products, 67, 12, pp. 1975-9
Tan, M., Zhou, L., Huang, Y., Wang, Y., Hao, X. & Wang, I. (2008). Antimicrobial activity of globulol isolated from the fruits of Euca-lyptus globulus Labill. Natural Product Re-search, 22, 7, pp. 569-575.
Usman, A., Mohammed, Y., Muhammed, H. O. & Zakari, A. H. (2020). Phytochemical Screening and Antioxidant Activity of Bala-nites Aegyptiaca Root Bark Extracts: Influ-ence of solvent. Communication in Physical Sciences, 5, 2, pp. 152-164.
Vasudevan, A., Vijayan, D., Mandal, P., Karthe, P., Sadasivan, C. & Haridas, M. (2012). Anti-Inflammatory Property of n-Hexadecanoic Acid: Structural Evidence and Kinetic As-sessment. Chemical Biology and Drug De-sign, 80, 3, pp. 434-439.
Coata, E. V., Dutraa, L. M., de Jesusa, H. C. R., Nogueiraa, P. C. D., Moraesa, V. R. D., Sal-vadorb , M. J., avalcantic, S. C. D., dos San-tosd, R. L. & Pratae, A. P. D. (2011). Chemi-cal composition and antioxidant, antimicro-bial, and larvicidal activities of the essential oils of Annona salzmannii and A. pickelii (Annonaceae). Natural Product Communica-tion, 6 , 6, pp. 907 – 912.
Ebenso, E. E., Eddy, N. O. & Odiongenyi, A. O. (2008). Corrosion inhibitive properties and adsorption behaviour of ethanol extract of Piper guinensis as a green corrosion inhibitor for mild steel in H2SO4. African Journal of Pure and Applied Chemistry, 4, 11, pp. 107-115.
Eddy, N. O,,Awe, F. E., Siaka, A., Magaji, L. & Ebenso, E. E. (2011b). Chemical infor-mation from GC-MS studies of ethanol ex-tract of Andrographis paniculata and their corrosion inhibition potentials on mild steel in HCl solution. International Journal of Electrochemical Sciences, 6, pp. 4316-4328.
Ekop, A. S. & Eddy, N. O. (2006). Comparative studies of the lipid characteristics and indus-trial potential of Coula edulis (African wal-nut and Terminalia catappa (indian almond) seeds. Global Journal of Pure and Applied Sciences, 12, 1, pp. 65-67.
Eddy, N. O., Ameh, P., Gimba, C. E. & Ebenso, E. E. (2011a). GCMS studies on Anogessus leocarpus (AL) gum and their corrosion inhi-bition potentials for mild steel in 0.1 M HCl. International Journal of Electrochemical Sciences, 6, pp. 5815-5829.
Ekundayo, O., Laakso, I., Adegbola, R.M., Oguntimein, B., Sofowora, A. & Hiltunen, R. (1988). Essential oil constit-uents of Ashanti pepper (Piper guineense) fruits (berries). Journal of Agriculture and Food Chemistry, 36, 5, pp. 880-882, https://doi.org/10.1021/jf00083a001
Haznedarogku, M. Z., Karabay, N. U. & Zey-bek, U. (2001). Antibacterial activity of Salvia tomentosa essential oil. Fitoterapia, 72, 7, pp. 829-831
Ikpeazu, O. V., Otuokere, I. E. & Igwe, K. K. (2020). Gas Chromatography–Mass Spec-trometric Analysis of Bioactive Compounds Present in Ethanol Extract of Combretum hispidum (Laws) (Combretaceae) Root. Communication in Physical Sciences, 5,3, pp. 325-337.
Imo, C., Yakubu, O. E., Imo, N. G., Udeg-bunam, I. S., Tatah, S. V. & Onukwugha, O. J. (2018
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