Chemical Information from GCMS of Ethanol Extract of Solanum melongena (Aubergine) Leaf

Authors

  • Emeka Chima Ogoko National Open University of Nigeria Jabi, FCT, Abuja, Nigeria

Keywords:

Solanum melongena leaf ethanol extract, phytochemicals, biological activity, application

Abstract

Communication in Physical Sciences, 2020 6(1): 658-668

Received 12 May 2020/Accepted 30 August 2020

Aubergine is often regarded as a local vegetable that is rarely consumed in Nigeria and other countries of the world. However, based on some nutritional data reported for this plant, the present study is aimed at investigating the phytochemical constituent of ethanol extract of this vegetable using GCMS. The results obtained indicated that ethanol extract of aubergine contains  1,1,3-trimethyl-cyclopentane (1.66%), alpha-undecane(2.21%),3,5-di-t-butylphenol(4.42%),6-methyl-1-heptanol (1.38%), dimethylmalononitrile (0.28%),  (5Z)-9-methyl-5-undecene (1.10%),metholene 2216 (11.60%), n-hexadecanoic acid (4.97%), ethyl stearate (2.21%), methyl linolelaidate (17.96%), methyl ester 9-octadecanoic acid (18.78%), 13Z)-13-octadecenal (8.29%), trans-3-oxabicyclo[4,4,0] decane -(6.63%), 5-methyl-1,2,3,6-tetrahydropyra -zine (1.66%), oleamide (2.49%), E-9-tetradecenal (5.52%) and  2,6-dimethyl-1,5-heptadiene (8.84%).  Most of the detected phytochemicals have several biological activities such as antimicrobial, anticancer, antiepileptic and other activities. Some were found to have some industrial roles indicating that much can be derived from this vegetable than it is currently known.

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Author Biography

Emeka Chima Ogoko, National Open University of Nigeria Jabi, FCT, Abuja, Nigeria

Department of Pure and Applied Sciences

References

Abdulazeez, A., Usman, A., Audu, S., Ibrahim, I. L., Kwokwu, S. I., Umar, M. T., Babatunde, J. & Uthman, A. (2020). Antioxidant assay and flavonoids of rind and seed of Citrullus lanatusl linn (water melon ). Communication in Physical Sciences, 5, 1, pp. 29-33.

Abdullahi, A. F., Maikaje, D. B., Denwe, S. D., & Muhammad, M. N. (2016). Evaluation of fermentation products of Eichhornia crassipes, Pistia stratiotes and Salvinia molesta. Agriculture and Biology Journal of North America, 7, 1, pp. 27-31.

Abulesu, M. (2019). Alzheimer’s disease theranostics. Elservier, doi.org/10.1016/C2018-0-00026-2.

Agarwal, A., Prajapati, R., Raza, S. K. & Thakur, L. K. (2017). GCMS analysis and antibacterial activity of aerial parts of Quisqualis indica plant extract. Indian Journal of Pharmaceutical Education and Research, 51, 2, pp. 329-336.

Ahmad, N., Roslan, A., Zareen, S., Zamri, N. & Akhtar, N. (2018). Preliminary phytochemica; screening, GC-MS profiling and in vitro evaluation of biological activities of Garcinia antroviridis root extracts. International Journal oof Advanced Research, 7, 1, pp. 53-61

Aikoye, A. O. (2020). Theoretical and biochemical information studies on compounds detected in GCMS of ethanol extract of Chromolaena odorate leaf. Communication in Physical Sciences, 5, 1, pp. 635-648.

Ajayi, E. O., Sadimenko, A. P. & Afolayan, A. J. Data showing chemical composition of the essential oils of the leaves of Cymbopogon citratus obtained by varying pH of the extraction medium. Data in Brief, 8, pp. 599-604.

Anbuseivi, S., Sravanthi, S. M. A., S., Nikhil, K.. & Roshini, E. (2019). Extraction of nasunin from different coloured egg plant peels and its phytochemical screening by GCMS. Research Journal of Pharmacy and Technology, 12, 6, pp. 2881-2884.

Arjinajarn, P., Pongchaidecha, A., Chueakula, N., Jaikunkao, K., Chatsudthipong,, Mahatheeranont, S.,Norkaew, O.,Chattipakom, N. & Lungkaphin, A. (2016). Riceberry bran extract prevents renal dysfunction and impaired renal organic anion transporter 3 (Oat3) function by modulating the PKC/Nrf2 pathway in gentamicin-induced nephrotoxicity in rats. Phytomedicine, 23, 14, pp. 1753-1763.

Ash, M. (2004). Handbook of preservatives. Synapse Information Resources Inc. Endicolt, New York.

Ashokkumar, V., Agila, E., Pandian, S., Salam, Z., Rengasamy, R. & Ani, F. N. (2014). Optimization and characterization of biodiesel production from microalgae Botryococcus grown at semi-continuous system. Energy Conversion and Management, 88, pp. 936-946.

Asogwa, F. C. (2017). Phytochemistry, anti-psoriatic and immunomodulatory properties of psorospermum febrifugum and harungana madagascariensis (hypericaceae). Ph.D Thesis, University of Nigeria, Nsukka.

Auria, M. D., Racioppi, R. & Velluzzi, V. (2008). A comparison of results obtained using liquid injection and headspace solid phase microextraction for crude oil analysis by GC with mass spectrometer detection. Journal of Chromatographic Sciences, 46, pp. 332-338

Boo, K. S., Park, K. C., Hall, D. R., Cork, A., Berg, B. G. & Mustaparta, G. (1995). (Z)-9-tetradecenal: a potent inhibitor of pheromone-mediated communication in the oriental tobacco budworm moth, Helicoverpa assulta . Journal of Comparative Physiology A, 177, pp. 695–699 (1995). https://doi.org/10.1007/BF00187628.

Canales, M., Hernández, T., Rodriguez-Monroy, M.A., Flores, C. M., Jiménez-Estrada, M., Hernández, L. B., Ramírez, J. J., Orozco, J., Eleno, M. G. & Martínez, K. E.(2011). Evaluation of the antimicrobial activity of Acalypha monostachya Cav. (Euphorbiales: Euphorbiaceae). African Journal of Pharmacy and Pharmacology, 5, 5, pp. 640-6475.

Chandrasekaran, M., Kannathasan, K. & Venkatesalu, V. (2008). Antimicrobial activity of fatty acif methyl esters of some members of Chenopodiaceae. Seitschrift fur Natuforschung C, 63, 5-6, pp. 331-336.

Chandrasekaran, M., Kannathasan, K., A. & Venkatesalu, V. (2008). Antimicrobial activity of fatty acid methy esters of some members of Chenopodiaceae. Z. Naturforsch, 63c, pp. 331-336.

Chandrasekaran, M., Senthlkumar, A. & Venkatesalu, V. (2011). Antibacterial and antifungal efficacy of fatty acid methyl esters from the leaves of Isesuvium portulacastrum L. European Review for Medical and Pharmacological Sciences, 15, 7, 775-780

Chen, H. P., Peng, Y., Liu, G., Li, H., Gao, L.Q., Zhan, N. & Xie, Y. (2012). Dynamic changes of volatile components from developing seeds of Plukenetia volubilis. Scientia Silvae Sinica, 54,pp. 157-168.

Cheseto, X. C., Baleba, B. S., Tanga, C. M., Kelemu, S. & Torto, B (2020). Chemistry and sensory characterization of a bakery product prepared with oils from African edible insects. Foods, 9, 800; doi:10.3390/foods9060800.

Eddy, N. O, Ekop, A. S. & Udofia, P. G. (2004). Effect of processing on the elemental composition of beans. Proc. of the 28th Annual Conference of the Nigerian Institute of Food Science and Technology. Edited by Adegoke, G. O., Sanni, L. O., Falade, K. O. and Uzo-peters, Uwaegbute, A. C. 109-112.

Eddy, N. O. & Odiongenyi, A. O. (2010). Corrosion inhibition and adsorption properties of ethanol extract of Heinsia crinata on mild steel in H2SO4. Pigment and Resin Technology 38, 5, pp. 288-295

Eddy, N. O. & Udoh, C. L. (2005). Proximate evaluation of the nutritional value of some soup thickeners. CHEMCLASS Journal, 2, pp. 12-14.

Eddy, N. O., Awe, Femi & Ebenso, E. E. (2010). Adsorption and inhibitive properties of ethanol extracts of leaves of Solanum melongena for the corrosion of mild steel in 0.1M HCl. International Journal of Electrochemical Science, 5, pp. 1996-2011.

Eddy, N. O., Ameh, P., Gimba, C. E. and Ebenso, E. E. (2011b). GCMS studies on Anogessus leocarpus (AL) gum and their corrosion inhibition potentials for mild steel in 0.1 M HCl. International Journal of Electrochemical Sciences, 6, pp. 5815-5829.

Eddy, N. O., Ekwumengbo, P. A. & Mamza, P. A. P. (2009). Ethanol extract of Terminalia catappa as a green inhibitor for the corrosion of mild steel in H2SO4. Green Chemistry Letters and Review, 2, 4, pp. 223-231.

Eddy, N. O., Ita, B. I., Dodo, S. N. & Paul, E. D. (2011a). Inhibitive and adsorption properties of ethanol extract of Hibiscus sabdariffa calyx for the corrosion of mild steel in 0.1 M HCl. Green Chemistry Letters and Review, 5, 1, pp. 43-53.

European Food Safety Authority (2014). Conclusion on the peer review of the pesticide risk assessment of the active substance Straight Chain Lepidopteran Pheromones. EFSA Journal, 12, 1, pp. 524-537. doi:10.2903/j.efsa.2014.3524.

Fidrianny, I., Winarshi, S. & Ruslan, K. (2017). Phytochemical content and antioxidant potential of different organs of egg plant (Solanum melongena L) grown in West Java-Indonesia. Asian Journal of Pharmaceutical and Clinical Research, 10, 8, pp. 144-149.

Gao, Y. Q., Guo, L. Y., Meng, X. X., Zhang, L. N. & Yang, G. D. (2018). The optimal GC-MS analysis of essential oil (fresh, dried and bud) and aroma enhanced by β-glucosidase on Aesculus chinensis flowers. Forest By-product and Specialty in China, 8, 5, pp. 1-4.

Guevara-Avendano, E., Adriana Bejarano-Bolivar, A. & Kiel-Martinez, A. 2019). Avocado rhizobacteria emit volatile organic compounds with antifungal activity against Fusarium solani, Fusarium sp. associated with Kuroshio shot hole borer, and Colletotrichum gloeosporioides. Microbiological Research, 219, pp. 74–83.

Hunziker, L., Boenisch, D., Groenhagen, U., Bailly, A., Schulz, S. & Weisskopf, L. (2015). Pseudomonas Strains naturally associated with potato plants produce volatiles with high potential for inhibition of Phytophthora infestans. Applied Environmental Microbiology, 81, pp. 821–830.

Hunziker, L., Bonisch, D., Groenhagen, U., Bailly, A., Schultz, S. & Weisskopf, L. (015). Pseudomonas strains naturally associated with potato plants produce volatiles with potential for inhibition of phytophthora infestans. Applied and Environmental Microbiology, 81, 3, pp. 821-830.

Igwe, K. K., Nwankudu, O. N., Ijioma, S. N., Madubuike, A. J. & Achi, N. K. (2016). Screening for secondary metabolites in Huru crepitans bark ethanol extract using GCMS analysis: A preliminary study approach. Journal of Science and Technology Advances, 1, 2, pp. 64-71.

Ikpeazu, O. V., Otuokere, E. I. & Igwe, K. K. (2020). Gas Chromatography–Mass Spectrometric analysis of bioactive compounds present in ethanol extract of Combretum hispidum (Laws) (Combretaceae) root. Communication in Physical Sciences, 5, 3, pp. 325-337.

Jumina, J., Lavendi, W., Singgih, T., Triono, S., Steven Kurniawan, Y., & Koketsu, M. (2019). Preparation of monoacylglycerol derivatives from Indonesian edible oil and their antimicrobial assay against Staphylococcus aureus and Escherichia coli. Scientific reports, 9, 1, pp. 10941. https://doi.org/10.1038/s41598-019-47373-4.

Kahriman, N., Tosun, G., Terzioglu, S., Karaoglu, S. A. & Yayh, N. (2011). Chemical composition and antimicrobial activity of the essential oil from the flower, leaf and stem of Senecio pandurifolus. Record of Natural Product, 5, 2, pp. 82-91.

Khiralla, A., Spina, R., Varbanov, M., Philippot, S., Lemiere, P., Slezack0Deschaumes, S., Andre, P., Mohamed, I., Yagi, S. M., & Laurain-Mattar, D. (2020). Evaluation of antiviral, antibacterial and antiproliferative activities of the endophytic fungus Curvularia papendorfi and isolation of a new polyhroxuacid. Microorganisms, 8, 1353; doi:10.3390/microorganisms8091353.

Kim, B., Kim, H. M., Kang, S., Kim, J., Jeon, Y. G., Park, K. Y., Lee, I. & Han, A. (2020). Composition and antioxidant activities of volatile organic compounds in radiation-bred Coreopsis cultivars, Plant, 9, 717; doi:10.3390/plants9060717

Kong, W., Li, P., Wu, X., Wu, T. & Sun, X. Forest tree associated bacterial diffusible and volatile organicncompounds against various phytopathogenic fungi. Microorganism, 8, 590; doi:10.3390/microorganisms8040590

Konoz, E., Abbasi, A., Parastar, H., Moazeni, R. S. & Jalali-Heravi, M.(2015). Analysis of olive fruit essential oil: Application of gas chromatography-mass spectrometry combined with chemometrics. International Journal of Food Properties, 18, 2, pp. 316-331.

Lazarevic, J. S., Palic, R. M., Radulovic, N. S., Tistic, N. R. & Stojanovic, G. S. (2010). Chemical composition and screening of the antimicrobial and antioxidative activity of extract of Stachys species. Journal of the Serbian Chemical Society, 75, 10, pp. 1347-1359.

Li, H., Zhang, S., Yu, X., Feng, X., Yamamoto, Y. & Bao, M. (2020). Rhodium (III) catalysed aromatic C-H cyanation with dimethylmalononitrile as cyanating agent. Chemical Communication, doi.org/10.1039/D0CC01497D

Lima, B. López, S., Luna, L., Agüero, M. B., Aragón L, Tapia, A., Zacchino, S., Lopez, M. L., Zygadlo, J. & Feresin, G. E. (2011). Essential oils of medicinal plants from the central andes of Argentina: chemical composition, and antifungal, antibacterial, and insect-repellent activities. Chemical Biodiversity, 8, 5, pp. 924- 936.

Lin, B. (2009). Complementary and alternative therapies and the aging population. Pp. 229-274, doi.org/10.1016/B978-0-12-374228-5.00012-3.

Luescher, M. U. (2019). Encyclopedia of reagents for organic synthesis. John Willey and Sons, Ltd. doi.org/10.1002/047084289X.rn02054

Macleod, A. J. & De Troconis, N. C. (1983) Aroma volatiles of Augbergine (Solanum melongena). Phytochemistry, 22, 9, pp. 2077-2079.

Mata, J., Castro, V & Chinchilla, G. (2018). Costa rican cashew (Anacardium occidentale L): Essential oils, carotenoids and bromatological analysis. American Journal of Essential Oils & Natural Products, 6, 3, pp. 1-9.

McDonnell, G., & Russell, A. D. (1999). Antiseptics and disinfectants: activity, action, and resistance. Clinical microbiology reviews, 12, 1, pp. 147–179.

Meiw, E. L., Zeng, Y. B., Liu, J &, Dai, H. F. (2007). GC-MS analysis of volatile constituents from five different kinds of Chinese eaglewood. Journal of Chines Medicinal Materials, 30, pp. 551-555.

Mikautadze, E., Avaliani, N., Kuchiashvili, N., Nozadze, M., Kiguradze, T., Pkhakadze, V., Mamulaishvili, I., Mikeladze, E. & Solomonia, R. (2008). Anti-epileptic properties of oleamide. BMC Proceeding, 2, 42, https://doi.org/10.1186/1753-6561-2-s1-p4.

Mills, L. R. & Rousseaux, S. A. L. (2019). A one pot electrophilli cyanation functionalization strategy for the synthesis of disubstituted malononitriles. Tetrahedron, 75, 32, pp. 4298-4306.

Mohan, M, & Krishna, M. P. (2019) Identification of Phytochemical Constituents of Michelia nilagirica Leaves. Journal of Phytochemistry Biochemistry, 3,115, pp. 1-5.

Montgomery, J. H. Groundwater chemicals desk reference. CRC Press, Taylor and Francis Group, p. 407

Nazeam, J. A., El-Hefnawy, H. M., Omran, G. & Singab, A. (2018). Chemical profile and antihyperlipidemic effect of Portulaca oleracea L. seeds in streptozotocin-induced diabetic rats. Natural Product Research, 32, pp. 1484-1488.

Nguyen, T., Delalande, O., Rouaud, I., Ferron, S., Chaillot, L., Pedeux, R. & Tomasi, S. (2018). Tert-butylphenolic derivatives from paenibacillus odorifer- A case study of bioconversion. Molecules, 23, 8, 1951; doi:10.3390/molecules23081951

Nwafor, A., Nworah, D. C. (2015). Adienbo, M. O. (2015). High-performance Thin-layer Chromatography (Hptlc) Fingerprint Profile of Hydromethanolic Chloroform Extract of Xylopia Aethiopica (Dunal) A. Rich (Annonaceae) Fruits. BMR Phytomedicine, 2, 1, pp. 1-8.

Okwu, D. B. & Ighodaro, B. U. (2009). GC-MS evaluation of the bioactive compounds and antibacterial activity of the oil fraction from the stem barks of Dacryodes edulis G. International Journal of Drug Development and Research, 1,1, pp. 117-125.

Pan, W. G., Li, Y., Zhu, X. Y., Zhu, Y. L., Li, Y. H. & Luo, P. (2012). GC-MS analysis of volatile oil from Hedyotis lancea. Chin. J. Exp. Tradit. Med. Formulae 2012, 18, pp.130–134.

Purewal, M. (2012). Derivation of petroleum hydrocarbon wildlands criteria for British Columbia. M.Sc. Thesis, Simon Fraser University

Rathna , J., Bakkiyaraj, D. & Pandian, S. K. (2016). Anti-biofilm mechanisms of 3,5-di-tert-butylphenol against clinically relevant fungal pathogens. Biofouling. 32, 9, pp. 979-993.

Reeves, J. T., Malapit, C. A., Buono, F. G., Sidhu, K. P., Marsini, M. A., Sader, O. A., Fandrick, K. R., Busacca, C. A. & Senanayake, C. H. (2015). Transnitrilation from dimethylmalonitrile to aryl grgnard and lithium reagents: A practical method for aryl nitrile synthesis. Journal of American Chemical Society, 137, 29, pp. 9481-9488.

Rigano, D., Formisano, C., Rosselli, S., Badalamenti, N. & Bruno, M. (2020). GC and GCMS analysis of volatile compounds from Ballota nigra subsp uncinate collected in aeolian Island, Sicily) Southern Italy). Natural Product Communication, 15, 4, pp. 1-7.

Sohani, M., Solanke, B. & Tawar, M. G. (2019). Phytochemical information and pharmaceutical activities of eggplant (Solanum melongena L) : A complementary review. EAS Journal of Pharmacy and Pharmacology, 1, 5, pp. 106-114.

Suresh, A., Praveenkumar, R., Thangarj, R., Lewis, F., Naldev, E., Shanasekaran, D. & Thajuddin, N. (2014). Microalgal fatty acid methyl ester, a ew source of bioactive compounds with antimicrobial activity. Asian Pacific Journa;l of Tropical Diseases, 4, 2, pp. S979-S984.

Tagele, S. B., Lee, H. G., Kim, S. W. & Lee, Y.S.(2019). Phenazine and 1-Undecene producing Pseudomonas chlororaphis subsp. aurantiaca Strain KNU17Pc1 for growth promotion and disease suppression in Korean maize cultivars. Journal of Microbiology and Biotechnology,, 29, pp. 66–78.

Tanner, F. W. & Wilson, F. L. (1943). Germicidal action of aliphatic alcohols. Proceeding of Society of Experimental Biomedicine, 52, pp. 138-140.

Vanitha, A., Kalimuthu, K., Chinnadurai, V., Sharmila, Y.& Prabakaran, R. (2016). GCMS analysis of leaf and salt stress callus of eggplant (Solanum melongene L). British Journal of Pharmaceutical Research, 14, 6, pp. 1-11.

Vasudevan, A., Vijayan, D., Mandal, P., Karthe, P., Sadasivan, C. & Haridas, M. (2012). Anti-Inflammatory Property of n-Hexadecanoic Acid: Structural Evidence and Kinetic Assessment. Chemical Biology and Drug Design, 80, 3, pp. 434-439.

Yehye, W. A., Abdul Rahman, N., Alhadi, A. A., Khaledi, H., Ng, S. W. & Ariffin, A. (2012). Butylated hydroxytoluene analogs: Synthesis and evaluation of their multipotent antioxidant activities. Molecules, 17, pp. 7645-7665.

Yuan, S. J., He, X. S., Yuan, X. H. & Huang, Y. (2019). Antioxidant activity evaluation and low-polarity components analysis of Coriolus versicolor and Trametes robiniophila. Science and Technology in Food Industry, 40, pp. 1–5.

Zayed, M. Z., Ahmad, F. B., Ho, W. & Pang, S. (2014). GCMS analysis of phytochemical constituents in leaf extracts of Neilamarcjia cadamba (Rubiacea) from Malaysia. International Journal of Pharmacology and Pharmaceutical Science, 6, 9m pp. 123-127.

Zhang, J. P., Salcedo, C., Fang, Y. L., Zhang, R. J. & Zhang, Z. N. (2012). An overlooked component: (Z)-9-tetradecenal as a sex pheromone in Helicoverpa armigera. Journal of Insect Physiology, 58, 9, pp. 1209-1216.

Zhou, J. Y., Zhao, X. Y. & Dai, C. C. (2014). Antagonistic mechanism of endophytic Pseudomonas fluorescens against Anthelia rolfsii. Journal of Applied Microbiology 117, 1144—1158.

Ziakas, G. N., Rekka, E. A., Gavalas, A. M., Eleftheriou, P. T. & Kourounakis, P. N. (2006). New analogues of butylatedhydroxytoluene as anti-inflammatory and antioxidant agents. Biooranic Medicinal Chemistry, 14,pp. 5616–5624.

Zubair, M., Bibi, Z., Rizwan, K., Rasool, N., Zahoor, A. F. & Riaz, M. (2013). In vitro antimicrobial and haemolytic studies of Bambusa arundinaceae leaves. Journal of Applied Pharmaceutical Science, 3, 4, pp. 111-115

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2020-09-10