Isolation and Characterization of Stigmasterol and Β-Sitosterol from the leaves of Emilia coccinea (Sims) G.Don

Authors

  • Ugochukwu Clinton Akwada Michael Okpara University of Agriculture Umudike, P.M.B. 7267 Umuahia, Abia State, Nigeria
  • Okenwa Uchenna Igwe Michael Okpara University of Agriculture Umudike, P.M.B. 7267 Umuahia, Abia State, Nigeria
  • Friday Chisom Michael Okpara University of Agriculture Umudike, P.M.B. 7267 Umuahia, Abia State, Nigeria
  • Juliet Chiamaka Ibe – Diala Michael Okpara University of Agriculture Umudike, P.M.B. 7267 Umuahia, Abia State, Nigeria

Keywords:

Emilia coccinea, extraction, stigmasterol and β-sitosterol, characterization

Abstract

Communication in Physical Science 2020, 6(2):883-868

Authors: Ugochukwu Clinton Akwada*, Okenwa Uchenna Igwe, Friday Chisom and Juliet Chiamaka Ibe - Diala

 Received 27 November 2020/Accepted 27 December 2020

In view of its unique medicinal value and other applications, stigmasterol and β-sitosterol were isolated from    Emilia coccinea leaves. Extraction of the compounds from the plant was carried out using Soxhlet apparatus, while column and thin layer chromatographic techniques were used for isolation and purification, which afforded white crystalline powder. Structural elucidation using 1H-NMR, DEPT, COSY, HSQC, and HMBC followed by comparison, with literature values confirmed the isolated compounds as stigmasterol and β-sitosterol. The isolated compounds may contribute to the medicinal properties of E. coccinea. This is the first isolation of stigmasterol and β-sitosterol from E. coccinea.

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Author Biographies

Ugochukwu Clinton Akwada, Michael Okpara University of Agriculture Umudike, P.M.B. 7267 Umuahia, Abia State, Nigeria

Department of Chemistry

Okenwa Uchenna Igwe, Michael Okpara University of Agriculture Umudike, P.M.B. 7267 Umuahia, Abia State, Nigeria

Department of Chemistry

Friday Chisom, Michael Okpara University of Agriculture Umudike, P.M.B. 7267 Umuahia, Abia State, Nigeria

Department of Chemistry

Juliet Chiamaka Ibe – Diala, Michael Okpara University of Agriculture Umudike, P.M.B. 7267 Umuahia, Abia State, Nigeria

Department of Chemistry

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Published

2020-12-30

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Vol. 6 No. 2 (2020): VOLUME 6(ISSUE 2)

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