Human Health Risk Assessment of Pesticide Residues in Solanum lycopersicum Fruit Sold in Lagos Metropolis, South-West Nigeria

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Kelle Henrietta Ijeoma
Oluade Oludare Abiola
Achem Daniel

Abstract

Communication in Physical Sciences 2020, 5(4): 533-532


Received 20 June 2020/Accepted 19 July 2020


Tomato is a vegetable that is eaten all over the world including Nigeria and in order to control infestation by pests, most tomato farmers use pesticides that may impart harmful effect on human. Consequently, this study was designed to assess pesticides residues and associated health risks in tomatoes sold in Lagos state. The result obtained indicated the presence of alpha and delta lindane, heptachlor, heptachlor epoxide, endrin, endosulfan, endosulfan sulphate and ether. Mean concentrations (mg/kg) and estimated daily intake (EDI) (mg/kg/day) of the pesticide residues were in the range of 0.0042 to 0.336 mk/kg and 7.5E- 6 to 2.3E-4 mg/kg/day respectively. The hazard quotient (HQ) ranged from 0.00024 to 17.77, while the hazard indices range from 1.00 to 18.92. The incremental lifetime cancer risk (ILCR) for the pesticide residues ranged from 5E- 5 to 2.1E- 3. The mean concentration of most of the pesticide residues in the tomato samples were above their maximum residue limit (MRL) while some had estimated daily intake (EDI) above their established acceptable daily intake (ADI) and  hazard quotients  (HQ) above their safe value. The hazard indices (HI) and Incremental lifetime cancer risk (ILCR) for the pesticide residues were above their safe values. The results and findings of the study indicate that there is need for continuous monitoring of pesticides residues in tomatoes and education of farmers on the uses of pesticides.

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Author Biographies

Kelle Henrietta Ijeoma, Faculty of Science, National Open University of Nigeria, Jabi, Abuja, Nigeria

Chemistry Unit, Department of Pure and Applied Sciences

Oluade Oludare Abiola , Faculty of Science, University of Lagos, Akoka, Lagos State, Nigeria

Department of Chemistry

Achem Daniel , Faculty of Science, University of Lagos, Akoka, Lagos State, Nigeria

Department of Chemistry

References

Abolusoro, P.F., Oginjimi, S.I. & Abolusoro, S.A. (2014). Farmers perception on the strategies for increasing tomato production in Kabba-Bunu Local Government Area of Kogi State, Nigeria. Agrosearch, 14, 2, pp. 144 – 153.

ATSDR (2007). Agency for Toxic Substances and Disease Registry Toxicological Profile for Heptachlor and Heptachlor Epoxide. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Services.

ATSDR, (2011), Endrin, Agency for Toxic Substances and Disease Registry.

https://www.atsdr.cdc.gov/substances/toxsubstance.asp?toxid=114

ATSDR (2005), Toxicological profile for Alpha-, Beta-, Gamma- and Delta- Hexachlocyclohexane, U.S Department of Health and Human Services, Public Health Services, Agency for Toxic Substances and Disease Registry.

ATSDR (2015), Toxicological profile for endosulfan, U.S Department of Health and Human Services, Public Health Services, Agency for Toxic Substances and Disease Registry.

Endrin-Wiley online Library https://onlinelibrary.wiley.com/doi/pdf/10.1002/3527600418.mb7220e0018

Escarlet, T.D.S., Dayane, E.S. and Anizio, M.F. (2018). Development of a methodology for the determination of pesticide residues in caja-manga pulp (spondias dulcis L.) using solid – liquid extraction with low-temperature portioning. Journal of Chemistry, Article ID 6012503, doi.org/10.1155/2018/6012503.

European Commission (2017), Guidance Document on Analytical Quality Control and Method Validation Procedures for Pesticides Residues Analysis in Food and Feed (SANTE/11813/20170) document.

European Union current MRL; https://ec.europa.eu/food/plant/pesticides/eu-pesticides-database/public/?event=pesticide.residue.selection&language=EN

Fang-Bo, Y., Ali, S.W., Jing-Ya, S & Lin-ping, L. (2012). Isolation and characterization of an endosulfan – degrading strain, stenotrophonomas sp. LD-6, and its potential in soil bioremediation. Polish Journal of Microbiology, 61, 4, pp. 257 – 262.

FAO/WHO, Codex Pesticides Residues in Food Online Database, CODEX ALIMENTARIUS INTERNATIONAL FOOD STANDARDS, http://www.fao.org/fao-who-codexalimentarius/codex-texts/dbs/pestres/en/

FAO (2011). Food and Agriculture Organisation of the United Nations.

http://www.fao.org/land-water/databases-and-software/crop-information/tomato/en/

Accessed 3/3/2020

FAO (2013). Food and Agriculture Organisation of the United Nations.

www.fao.org/3/19747EN/i9747en.pdf Accessed 3/3/

(FMAWR) (2007, Federal Ministry of Agriculture and Water Resources . Pest Management Plan (PMP) for FADAMA III PROJECT. http://documents.vsemirnyjbank.org/curated/ru/147331468145168775/pdf/E16490v20Pest0Management0Plan.pdf Accessed 4/4/2020

Gerba, C.P. (2019). Risk assessment, in: Brusseau, M.L., Pepper, I.L and Gerba, C.P. (Eds), Environmental and Pollution Science. Elsevier Inc, pp. 541 – 563.

Jozsef, P., Karoly, P. & Janos, N. (2013). Pesticide productivity and food security. A review. Agronomy for Sustainable Development, 33, 243 – 255.

Kelle, H.I. Ogoko, E.C., Achem, D. & Ousherovich, S.A. (2020). Health risk assessment of heavy metals in some rice brands imported into Nigeria. Communication in Physical Sciences, 5, 2, 210 – 222.

McNaught, A.D. & Wilkinson, A. (1997). Compendium of Chemical Terminology, 2nd Ed. Blackwell Scientific, https://doi.org/10.1351/goldbook.

Mladenovic, J. Acamovic, G. Kovil, R. Pavlovic, R. Zoravkovic, M. Girek, Z. & Zaravkovic, J. (2014), The Biologically Active(bioactive) Compounds in Tomato (Lycopersicon Esculentum Mill.) as a function of genotype. Bulgarian Journal of Agricultural Science, 20, 4, pp. 877 – 882.

NAFDAC, (2016 a). List of approved pesticides by NAFDAC http://documents.worldbank.org/curated/en/115291468099839070/pdf/SFG2220-EA-P157899-Box396258B-PUBLIC-Disclosed-5-20-2016.pdf

NAFDAC, (2016 b). National Agency for Food and Drug Administration and Control, List of banned pesticides in Nigeria. https://www.nafdac.gov.ng/wpcontent/uploads/Files/Resources/Directorate_Resources/VMAP/LIST-OF-BANNED-PESTICIDES.pdf Accessed 4/4/2020

Paolo, D., Bianchi, G., Lo Scailo, R., Morelli, C. F., Rabuffetti M., & Speranza, G. (2018). The Chemistry behind Tomato Quality. Natural Product Communication, 13, 9, pp. 1225 – 1232.

Pimentel, D. (2005). Environmental and economic costs of the application of pesticides in the United States. Environ Sus Dev, 7, pp, 229 – 252.Singh, V.K., Singh, A.K. & Kumar, A. (2017). Disease management of tomato through PGPB: Current trends and future perspective, Biotechnology., 7, 4, pp. 255 -259.

Tijani, A. A. & Sofoluwe, N. A. (2016). Factors determining the extent of pesticide use in Nigerian farms. Ife Journal of Science, 18, 4, pp. 981 – 991.

Viskelis, P., Radze, A. Urbonaviciene, D, Viskelis, R. Karkleliene & Bobinas, C. (2015,) Biochemical Parameters in Tomato Fruits from different Cultivars as Functional Foods for Agricultural, Industrial and Pharmaceutical Uses. IntechOpen Books,

WHO, (2017), Country assignments to the 13 proposed GEMS/ food consumption cluster diets Geneva, Available from: http://www.who.int/ foodsafety/chem/countries.pdf

WHO, (2012). https://www.who.int/en/news-room/fact-sheets/detail/pesticide-residues-in-food Acessed 4/4/2020

WHO (2018). Pesticides. https://www.who.int/topics/pesticides/en/ Acessed 4/4/2020

World Bank. (2018). The World Bank, Life Expectancy at Birth, Total (years) – Nigeria. https://data.worldbank.org/indicator/SP.DYN.LE00.IN?locations=NG (accessed 15 April 2020).

United States Environmental Protection Agency. (2000). Supplementary guidance for conducting health risk assessment of chemical mixtures. Risk Assessment Forum Technical Panel [EPA/630/R-00/002]. Washington, DC: United Environmental Protection Agency States.

US EPA, Endosulfan, CASRN 115-29-7, Integrated Risk Information System (IRIS) Chemical Assessment Summary, U.S. Environmental Protection Agency, National Center for Environmental Assessment.

U SEPA, Endrin; CASRN 72-20-8, Integrated Risk Information System (IRIS) Chemical Assessment Summary, U.S. Environmental Protection Agency, National Center for Environmental Assessment.

U SEPA, Heptachlor; CASRN 76-44-8, U.S. Environmental Protection Agency , National Center for Environmental Assessment.

USEPA (2005). Human health risk assessment protocol, Chapter 6: Quantifying exposure, multimedia planning and permitting Division, Office of Solid waste, Center for Combustion Science and Engineering. https://www. weblakes.com/products /iraph/resources hhrap /chp_6.pdf (Accessed 27 April 2020).

US EPA, Lindane; gamma-Hexachlorocyclohexane (gamma-HCH); CASRN 58- 89-9, Integrated Risk Information System (IRIS) Chemical Assessment Summary, U.S. Environmental Protection Agency , National Center for Environmental Assessment.

US EPA (2014). Overview of human health risk assessment. Office of Research and development, National Center for Environmental Assessment, National Institute of Environmental Health Science Superfund Research Program. https://www.niehs.nih.gov/research/supported/centers/srp/assets/docs/srp_risk_assessment_ arzuaga_508.pdf (Accessed 12 April, 2020).

US EPA (2002), Provisional Peer-Reviewed Toxicity Values for Endrin. U.S. Environmental Protection Agency, Washington, DC, EPA/690/R-02/007F.

US EPA (2013). Provisional peer – reviewed toxicity values for endosulfan sulphate (CASRN 1031-07-8), Superfund Health Risk Technical Support Center, National Center for Environmental Assessment, Office of Research and Development, U.S Environmental Protection Agency.