Phytochemical Profiling of 30% Acetone Honeybee Crude Extract Collected From Ondo West Forest, Ondo State, Nigeria

Authors

  • Akens Hamilton-Amachree Federal University Otuoke, Bayelsa State, Nigeria

Keywords:

Crude honeybee residue, phytoconstitutions, quercetin, kaempferol

Abstract

Communication in Physical Sciences, 2022, 8(4):647-651

Akens Hamilton-Amachree

Received: 02 June 2022/Accepted 20 December  2022

Chemical data on the phytochemistry of crude honeybee residue may be useful in the development of therapeutic substances for alternative medicines. This has necessitated the present study, which involves the probing of 30% acetone crude extract of crude honeybee residue (collected from the Ondo North forest of Ondo state, Nigeria). The crude honeybee residue was assayed for its phytoconstitutions via qualitative phytochemical screening and quantitatively through high-pressure liquid chromatography(HPLC).   The results obtained from the phytochemical investigation indicated the presence of alkaloids, terpenoids, flavonoids, phenols and glycosides. However, HPLC spectrum reveals the presence of quercetin (27.84%) and kaempferol (23.31%) showing retention times of 36.64 and 38.70 min respectively. The identified phytochemicals were the major constituents and are known for their medicinal significance.

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Author Biography

Akens Hamilton-Amachree , Federal University Otuoke, Bayelsa State, Nigeria

Department of Chemistry

References

Hamilton-Amachree, A. & Odokwo, O.E. (2022). Phytoconstitution, anti-oxidant and iron chelating profiling of 30% acetone extract of crude honey residue in Obudu Local Government Area of Cross Rivers State, Nigeria. World Scientific News, 172, pp.165-178.

Abel, A.A. & Banjo, A.D. (2012). Apitheraphy in Southern Nigeria: An assessment of therapeutic potentials of some honeybee products. Journal of Pharmaceutical and Biomedical Sciences, 2,2, pp. 9-15.

Bankova, V., Castro, S.L. & Marcucci, M.C. (2000). Propolis: Recent advances in Chemistry and plant origin. Apidologie, 31, pp. 3-15.

Alvarez-Suarez, J.M., Tulipani, S., Romandini, S., Bertoli, E. & Battino, M. (2010). Contribution of honey in nutrition and human health: a review. Mediterr J Nutr Metab., 3, pp.15-23.

Jose, M.S. & Vassya, B. (2010). Propolis: Is there a potential for development of new drugs. Journal of Ethnopharmacology, 133, pp. 253-260.

Feng, L., Suresh, A., Hongyan, Z., Yasuhiro, T., Hiroyasu, E. & Shigetoshi, K. (2009). Chemical constituents of propolis from Myannar and their preferential cytotoxic against a human pancreatic cancer cell line. Journal of Natural Products, 72, pp. 1283-1287.

Odokwo, E. O. & Salawu, R. A. (2021). Chemical and biological profiling of n-hexane extract of crude honeybee residue. World Scientific News, 152, pp. 69-81.

Dhar, N. B. & Shoskes, D. A. (2007). New therapies in chronic prostatis. Curr Urol Rep., 8, 4, pp. 313-318.

Edwards, R. L. Lyon, T. & Litwin, S. E. (2007). Quercetin reduces blood pressure in hypertensive subjects. J Nutr 137, pp. 2405-2411.

Kumar, S. & Pondey, A.K. (2013). Chemistry and activities of flavonoids: An overview. Scientific World Journal, 2013, pp. 1-16.

Loke, W.M., Hodgson, J. M., Proudfoot, J. M., McKinley, A. J., Puddey, I. B. & Croft, K. D. (2008). Pure dietary flavanoids quercetin and (-)-epicatechin augment nitric oxide products and reduce endothelin-1 acutely in healthy men. Am J Clin Nutr 88, 4, pp. 1018-1025.

McAnulty, S. R., McAnulty, L. S., Nieman, D. C., Quindry, J. C., Hosick, P. A., Hudson, M. H., Still, L., Henson, D. A., Milne, G. L., Morrow, J. D., Dumke, C. L., Utter, A. C.,Triplett, N. T. & Dibarnardi, A. (2008). Chronic quercetin ingestion and exercise induced oxidative damage and inflammation. Appl Physiol Nutr Metals 33, 2, pp. 254-262.

Beatty, E. R. O’Reilly, J. D., England, T. G., McAnlis, G. T., Young, I. S., Geissler, C. A., Sanders, T.A. & Wiseman, H. (2000). Effect of dietary quercetin on oxidative DNA damage in healthy human subjects. British Journal of Nutrition, 84, 6, pp. 919-925.

Boots, A. W., Haenen, G. R. & Bast, A. (2008). Health effect of quercetin: from antioxidant to nutraceutical. Eur J Pharmacol. 585, 2,3,pp. 325-337.

Murakami, A. Ashida, H. & Terao, J. (2008). Multitargeted cancer prevention by quercetin. Cancer Lett. 269, 2, pp. 315-325.

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Published

2022-12-30