Isolation and Characterization of Secondary Metabolite from the leaves Aspilia Africana (Pers.) C. D. Adams (Asteraceae)

Authors

  • Ahamefula A. Ahuchaogu

    Abia state University, Uturu. Abia State, Nigeria
    Author
  • Okenwa U. Igwe

    Michael Okpara university of Agriculture, Umudike, Abia State, Nigeria
    Author

Keywords:

Squalene, isolation and characterization, Aspilia Africana, MS and NMR

Abstract

Aspilia africana is a medicinal plant used traditionally for treating various diseases. Phytochemical investigation of the methanol extract of the leaves has led to the isolation of squalene (hexamethyl-2, 6, 10, 14, 18, 22-tetracosahexa-ene) from the leaves of A. Africana and is known to possess significant antimicrobial activity, it has not been known to be previously isolated from Aspilia Africana. The structure of the component was elucidated based on the NMR and MS techniques and by comparison of their experimental data with literature. The purified compound was obtained by chromatographic method.

Author Biographies

  • Ahamefula A. Ahuchaogu, Abia state University, Uturu. Abia State, Nigeria

    Department of Pure and Industry Chemistry

  • Okenwa U. Igwe, Michael Okpara university of Agriculture, Umudike, Abia State, Nigeria

    Department of Chemistry

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Published

2020-08-30

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