Chemical Information from GCMS Analysis of Acetone Extract of Piper guineense Leaves. Part 1

Abstract

Applications of plant leaves for various purposes is based on its chemical constituents which may include proximate, elemental, phytochemical, toxicant, amino acid and other toxicants. Knowledge of phytochemical constituents is significant for their pharmaceutical/medicinal values. This study was carried out to investigate the chemical constituents of acetone extract of Piper guineense leaves through phytochemical screening and GCMS analysis. Results obtained from phytochemical screening indicated the major constituents (those whose concentrations were greater than 1%) to include ,6-dimethyloxazolo(5,4-c)pyridazin-4-amine (31.80 %), 3-(1-methylethyl)-cyclohexene (20.99 %), 4-methoxy-N-(4-nitrobenzyl)-benzamide (12.82 %), alpha bisabolene (7.33%), 1,2,3,4,4a,5,6,8a-octahydro-7-methyl-4-methylene-1-(1-methylethyl)-napthalene (4.42 %), 3,7-diacetamidophenoxathin (4.10 %), 1,3,3-trimethyl tricyclo{2,2,1]heptane (2.98%), 3H-indazol-3-one (2.11%), 1H-indene,octahydro-1,7a-dimethyl-4-(1-methylethenyl)-1,4-methano-1H-indene (1.98%), piperidine (1.97%),2,4-disopropenyl-1-methyl-1-vinyl (1.70%), n-hexadecanoic acid (1.68%), eudesdma-4[14],11-diene (1.27%). The pharmaceutical values of the identified constituents were also analsed. The study reveals that acetone extract of Piper guneense contains constituents that are not visible with some other solvents