Chemical Information from GCMS Analysis of Acetone-Ethanol Ex-tract of Piper guineense Leaf. Part 2

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Onyeije Ugomma Chibuzo
Augustine Odiba Aikoye


Communication in Physical Sciences 2020, 5(4): 470-481

Received 25 June 2020/Accepted 29 July 2020

The need to know the different constituents of Piper  guineense  leaf extract through the use of different solvent is remarkable because solvents play significant role in the constituent that can be extracted from planr materials. GCMS analysis of Acetone-ethanol extract of  Piper guineense leaves indicated twenty one peaks which represented  2,3,6,7,7a-hexahydro-7a-methyl-5H-indene-5-one, alpha-cubebene, 1-ethenyl-1-methyl-2,4-bis(1-methylethenyl)-cyclohexane, caryophyllene, alpha caryophyllene, megastigma-7(E),9, 13-triene, eudesdma-4(14),11-diene, azulene, epsilon muurolene, di-t-butylacetylene, -cyclopentene -1-ethanol, 2,24-trimethyl, 2,6,6- trimethyl-3-(phenylthiol)cyclohep-4-enol, hexadecenoic acid, nonadecanoic acid, octadecanoic acid, cyclohexylidenecyclohexane,, pyrrolo[3,2-c]pyridine-4(5H)-one, 4,5-dihydrobenzo[1,2-c:3,4-c’]bis[1,2,5]oxadiazole, piperidine, 3,7-diacetamidophenoxathin and 4-(6-methoxy-3-mythyl-2-benzofuran)-3-buten-2-one respectively. The most abundant components of the extract was di-t-butylacetylene (17.36%) and ,5-dihydrobenzo[1,2-c:3,4-c’]bis[1,2,5]oxadiazole (12.95%). Most of the  identified compounds were reported to possess strong biological activities. Compounds that has not been reported from GCMS analysis of the plant leaves using other solvent were also observed which confirmed that the missed  solvent (acetone-ethanol) is more effective in extracting phytochemicals in Piper guineense leaves than either of the solvent


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Author Biographies

Onyeije Ugomma Chibuzo, Rhema University, 153-155 Aba Owerri Road P. M. B. 7021, Abia State, Nigeria

Department of Chemistry

Augustine Odiba Aikoye , University of Nigeria, Nsukka, Enugu State, Nigeria

Department of Pure and Industrial Chemistry


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