Chemical Information from GCMS Analysis of Acetone-Ethanol Ex-tract of Piper guineense Leaf. Part 2
Keywords:Piper guineense, leaves, acetone-ethanol ex-tract, biological activity, effect of solvent
Communication in Physical Sciences 2020, 5(4): 470-481
Received 25 June 2020/Accepted 29 July 2020
The need to know the different constituents of Piper guineense leaf extract through the use of different solvent is remarkable because solvents play significant role in the constituent that can be extracted from planr materials. GCMS analysis of Acetone-ethanol extract of Piper guineense leaves indicated twenty one peaks which represented 2,3,6,7,7a-hexahydro-7a-methyl-5H-indene-5-one, alpha-cubebene, 1-ethenyl-1-methyl-2,4-bis(1-methylethenyl)-cyclohexane, caryophyllene, alpha caryophyllene, megastigma-7(E),9, 13-triene, eudesdma-4(14),11-diene, azulene, epsilon muurolene, di-t-butylacetylene, -cyclopentene -1-ethanol, 2,24-trimethyl, 2,6,6- trimethyl-3-(phenylthiol)cyclohep-4-enol, hexadecenoic acid, nonadecanoic acid, octadecanoic acid, cyclohexylidenecyclohexane,, pyrrolo[3,2-c]pyridine-4(5H)-one, 4,5-dihydrobenzo[1,2-c:3,4-c’]bis[1,2,5]oxadiazole, piperidine, 3,7-diacetamidophenoxathin and 4-(6-methoxy-3-mythyl-2-benzofuran)-3-buten-2-one respectively. The most abundant components of the extract was di-t-butylacetylene (17.36%) and ,5-dihydrobenzo[1,2-c:3,4-c’]bis[1,2,5]oxadiazole (12.95%). Most of the identified compounds were reported to possess strong biological activities. Compounds that has not been reported from GCMS analysis of the plant leaves using other solvent were also observed which confirmed that the missed solvent (acetone-ethanol) is more effective in extracting phytochemicals in Piper guineense leaves than either of the solvent
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