Chemical Information from GCMS Analysis of Acetone-Ethanol Ex-tract of Piper guineense Leaf. Part 2
Keywords:
Piper guineense, leaves, acetone-ethanol ex-tract, biological activity, effect of solventAbstract
Communication in Physical Sciences 2020, 5(4): 470-481
Received 25 June 2020/Accepted 29 July 2020
The need to know the different constituents of Piper guineense leaf extract through the use of different solvent is remarkable because solvents play significant role in the constituent that can be extracted from planr materials. GCMS analysis of Acetone-ethanol extract of Piper guineense leaves indicated twenty one peaks which represented 2,3,6,7,7a-hexahydro-7a-methyl-5H-indene-5-one, alpha-cubebene, 1-ethenyl-1-methyl-2,4-bis(1-methylethenyl)-cyclohexane, caryophyllene, alpha caryophyllene, megastigma-7(E),9, 13-triene, eudesdma-4(14),11-diene, azulene, epsilon muurolene, di-t-butylacetylene, -cyclopentene -1-ethanol, 2,24-trimethyl, 2,6,6- trimethyl-3-(phenylthiol)cyclohep-4-enol, hexadecenoic acid, nonadecanoic acid, octadecanoic acid, cyclohexylidenecyclohexane,, pyrrolo[3,2-c]pyridine-4(5H)-one, 4,5-dihydrobenzo[1,2-c:3,4-c’]bis[1,2,5]oxadiazole, piperidine, 3,7-diacetamidophenoxathin and 4-(6-methoxy-3-mythyl-2-benzofuran)-3-buten-2-one respectively. The most abundant components of the extract was di-t-butylacetylene (17.36%) and ,5-dihydrobenzo[1,2-c:3,4-c’]bis[1,2,5]oxadiazole (12.95%). Most of the identified compounds were reported to possess strong biological activities. Compounds that has not been reported from GCMS analysis of the plant leaves using other solvent were also observed which confirmed that the missed solvent (acetone-ethanol) is more effective in extracting phytochemicals in Piper guineense leaves than either of the solvent
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References
Abass, R. K. (2018). Volatile oil composition of Ocimum basilicum (Rehan) leaf eextract and antibacterial activity against bacterial patho-gens in Sudan. Elixir Biosciences 125, pp. 52306-52308.
Agoramoorthy, G., Chandrasekaran, M., Venka-tesalu, V., & Hsu, M.J.. (2007). Antibacterial and antifungal activities of fatty acid methyl esters of the blind-your-eye mangrove from India. Brazilian Journal of Microbiology, 38, 4, pp. 739-742.
Al-Hajj, N. Q., Wang, H. X., Ma, C., Lou, Z., Bashari, M. & Thabit, R. (2014). Antimicro-bial and Antioxidant Activities of the Essen-tial Oils of Some Aromatic Medicinal Plants (Pulicaria inuloides-Asteraceae and Ocimum forskolei-Lamiaceae). Tropical Journal of Pharmaceutical Research, 13, 8, pp. 1287-1293
Arrhenius, T. S. (1982). Synthesis of iso-comene. Ph.D Thesis, Rice University.
https://hdl.handle.net/1911/15664.
Bakhite, E. A., Abd-Ella, A. A., El-Sayed, M. E. A. & Abdel-Raheem, S. A. A. (2017). Pyri-dine derivatives as insecticides. Part 2: Syn-thesis of some piperidinium and morpholini-um cyanopyridinethiolates and their insecti-cidal activity. Journal of Saudi Chemical So-ciety, 21, 1, pp. 95-104.
Costa, E. V., Dutra, L. M., de Jesus, H. C. R., Nogueira, P. C. D, Moraes, V. R. D.,Salvador, M. J., Cavalcanti, S. C. D., San-tos, R. L. C. D. & Prata, A. P. D. N. (2011). Chemical composition and antioxidant, anti-microbial and larvicidal activities of the es-sential oils of Annona salzmannii and A pick-elli (Annonacae). Natural Product communi-cation, 6, 6, pp. 907-912.
Ebenso, E. E., Eddy, N. O. & Odiongenyi, A. O. (2008). Corrosion inhibitive properties and adsorption behaviour of ethanol extract of Piper guinensis as a green corrosion inhibitor for mild steel in H2SO4. African Journal of Pure and Applied Chemistry, 4, 11, pp. 107-115.
Eddy, N. O. & Odiongenyi, A. O. (2010). Cor-rosion inhibition and adsorption properties of ethanol extract of Heinsia crinata on mild steel in H2SO4. Pigment and Resin Technolo-gy 38, 5, pp. 288-295
Eddy, N. O., Ameh, P., Gimba, C. E. & Ebenso, E. E. (2011b). GCMS studies on Anogessus leocarpus (AL) gum and their corrosion inhi-bition potentials for mild steel in 0.1 M HCl. International Journal of Electrochemical Sciences, 6. Pp. 5815-5829.
Eddy, N. O., Ita, B. I., Dodo, S. N. & Paul, E. D. (2011a). Inhibitive and adsorption properties of ethanol extract of Hibiscus sabdariffa ca-lyx for the corrosion of mild steel In 0.1 M HCl. Green Chemistry Letters and Review, 5, 1, pp. 43-53.
Ekop, A. S. & Eddy, N. O. (2006). Comparative studies of the lipid characteristics and indus-trial potential of Coula edulis (African wal-nut and Terminalia catappa (indian almond) seeds. Global Journal of Pure and Applied Sciences, 12, 1, pp. 65-67.
Erdem, B., Bagci, E., Dogan, G., Aktoklu, E. & Dayangac, A. Chemical composition and antimicrobial activities of essential oil and ethanol extract of Cyperus fuscus burs from Turkey. Tropical Journal of Pharmaceutical Research, 17, 8, pp. 1637-1643.
Guarrera, M., Turbino, L. & Rebora, A. (2001). The anti-inflammatory activity of az-ulene. Journal of European Academy of Dermatology and Venereology, 15, 5, pp. 486-487. doi:10.1046/j.1468-3083.2001.00340.x
Gupta, R. C. (2016). Nutraceuticals: efficacy, safety and toxicity. Elservier Inc, Nether-lands, https://doi.org/10.1016/C2014-0-01870-9.
Imo, C., Yakubu, O. E., Imo, N. G., Udeg-bunam, I. S., Tatah, S. V. & Onukwugha, O. J. (2018). Proximate, mineral and phyto-chemical composition of Piper guin-eense seeds and leaves. Journal of Biological Sciences, 18, pp. 329-337.
Kabiru, A. Y., Ibikunle, G. F., Innalegwu, D. A., Bola, B. M. & Madaki, F. M. (2016). In vitro antiplasmodial and analgesic effect of crude ethanol extract of Piper guineense leaf ex-tract in Albino mice. Sciencetica, https://doi.org/10.1155/2016/8687313
Manivannan, P., Muralitharan, G., & Balaji, N. P. (2017). Prediction aided in vitro analysis of octa-decanoic acid from Cyanobacterium Lyngbya sp. as a proapoptotic factor in elicit-ing anti-inflammatory proper-ties. Bioinformation, 13, 9, pp. 301–306.
Martins, C., do Nascimento, E. A., de Morais, S. A., de Oliveira, A., Chang, R., Cunha, L. C., Martins, M. M., Martins, C. H., Moraes, T.,
Rodrigues, P. V., da Silva, C. V., & de Aquino, F. J. (2015). Chemical Constituents and Evaluation of Antimicrobial and Cyto-toxic Activities of Kielmeyera coriacea Mart. & Zucc. Essential Oils. Evidence-based com-plementary and alternative medicine : eCAM, 2015, 842047. https://doi.org/10.1155/2015/842047
Mohiuddin, Y. G., Nathar, V. N., Axix, W. N. & Gaikwad, N. B. (2015). Chemoprofilling of volatile oil extracted from Artemisia ab-sinthium . using GCMS. International Journal of Innovative Pharmaceutical Sciences and Researc, 5, 12, pp. 143-154.
Mohiuddin, Y. G., Nathar, V. N., Axix, W. N. & Gaikwad, N. B. (2015). Chemo profiling of volatile oil extracted from Artemisia ab-sinthium . using GCMS. International Journal of Innovative Pharmaceutical Sciences and Researc, 5, 12, pp. 143-154.
Onyeije, U. C. & Okop, I. (2020). Chemical in-formation from GCMS analysis of acetone extract of Piper guineense leaves. Part 1. Communication in Physical Sciences, 5(4): 417-445.
Ojinnaka, M. C., Odimegwu, E. N. & Chidiebere, F. E. (2016). Comparative study on the nutrient and antinutrient composition of the seeds and leaves of Uziza (Piper guin-eense). IOSR Journal of Environmental Sci-ence, Toxicology and Food Technology, 10, 8, pp. 42-48.
Praskasia, P. P. & Nair, A. S. (2015). Chemical fingerprint of essential oil components from fresh leaves of Glycosmis pentaphylla (Retz.) Correa. The Pharma Innovation Journal, 3, 12, pp. 50-56.
Rahman, M. M., Ahmad, S. H., Mohamed, M. T. & Ab Rahman M. Z.Antimicrobial Com-pounds from Leaf Extracts of Jatropha cur-cas, Psidium guajava, and Andrographis pa-niculata . The Scientific World Journal, s http://dx.doi.org/10.1155/2014/635240
Rizwana, H. (2018). In vitro antibacterial and antifungal activity of some oils, chemical analysis and their FTIR studies. International Journal of Agriculture and Biology, 20, 7, pp. 1486-1496.
Sacchetti, G., Maietti, S., Muzzoli, M., Scaglianti. M., Manfredini, S., Radice, M. & Bruni, R. 2005). Comparative evaluation of 11 essential oils of different origin as func-tional antioxidants, antiradicals and antimi-crobials in foods, Food Chemistry, 91, pp. 621-632.
Sasikala, P., Jayaseeian, T., Azhagumadhavan, S., Padma, M., Senthikumar, S. & mani, P. (2019). Phytochemicals and GC–MS analysis of bioactive compounds present in ethanolic leaves extract of Taraxacum officinale (L). Journal of Drug Delivery and Therapeutics, 9. 1. Pp. 90-94.
Sun, Z., Chen, B., Zhang, B. & Hu, C. (2005). Four new eudesmanes from Caragana inter-media and their biological activities. Journal of Natural Products, 67, 12, pp. 1975-9
Wasswa, J. N., Omorodion, T. N., Avwioro, G. O & Asimiyu, O. S.(2017) Histological ef-fect of Piper guineense (Uziza) leaves on the liver of Wistar rats. International Journal of Research and Review, 4,3, p. 36-41.
Ye, M., Liu, D., Zhang, R., Yang, L. & Wang, J. (2012). Effect of hawk tea (Litsea coreana L.) on the number of lactic acid bacteria and flavour compounds of Yoghurt. Internation-al Dairy Journal, 23, 1, pp. 68-71.
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