Health Risk Assessment of Heavy Metals in some Rice Brands Imported into Nigeria
Keywords:
Rice, , heavy metals, hazard index, hazard quotient, , cancer riskAbstract
Communication in Physical Sciences 2020, 5(2): 210-222
Authors: Kelle Henrietta Ijeoma, Ogoko Emeka Chima, Achem Daniel and Ousherovich Shola Ayotunde
Received 29 April 2020/Accepted 26 May 2020
Rice is a major staple food in Nigeria and currently, the production capacity of the country cannot meet consumers; demand. Therefore, large quantities of rice are imported into the country without recourse to their heavy metal contents. Several research reports indicated that there is a likely possibility of heavy metal contamination of foreign rice and associated health hazards. Therefore, this study seeks to analyse foreign rice in Nigeria markets and identified their health implications. The result obtained indicated that mean concentrations of the heavy metal ions were Cd (0.0014 ± 0.00005 to 0.4322 ± 0.00005), Cr (0.0010 ± 0.00005 to 0.1080 ± 0.00005), As (0.0006 ± 0. 0001 to 0.1711 ± 0.0008), Ni (0.0007 ± 0.00001 to 0.8865 ± 0.00005), Hg (0.0024 ± 0.0001 to 0.0935 ± 0.001), Cu (0.0052 ± 0.00001 to 0.3208 ± 0.00005), Pb(0.0047 ± 0.00001 to 0.3974 ± 0.00001). Most of the imported rice brands have mean concentration (mg/kg) of the heavy metals below their maximum permissible limit (MPL) as set by FAO/WHO and Codex Alimentarius Commission (CAC). The hazard quotient (HQ) for the heavy metals in the imported rice brands range from 0.0006 (6 x 10–4) to 5.0 while their hazard index (HI) range from 1.2 – 9.31. Most of the imported rice brands (62.5 %) and all the rice brands (100%) had HQ and HI for the heavy metals greater than one respectively pointing to the, likelihood and high potential for non-carcinogenic risks. The cancer risk assessment value ranged from 8 x 10–6 to 1 x 103 which suggest probability of cancer risks.
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References
Abdul-Hamid, A., Sulaiman, R. R. R. & Saari, O.N. (2007). Preliminary study of the chemical composition of rice milling fractions stabilized by microwave heating. Journal of Food Composition and Analysis, 20, 7, 627-637.
Ali, H. & Khan, E. Ilahi, I. (2019). Environmental chemistry and ecotoxicology of hazardous heavy metals: environmental persistence, toxicity, and bioaccumulation. Journal of Chemistry,https://doi.org/10.1155/2019/6730305
Aoshima, K. (2016). Itai-itai diseases: Renal
tubular osteomalacia induced by environmental exposure to cadmium-historical review and perspectives. Soil Science and Plant Nutrition, 62, 4, pp. 319-326.
ATSDR (2005). Agency for Toxic Substances and Disease Registry. Toxicological profile for nickel. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service.https://www.atsdr.cdc.gov/toxprofiles/tp15.pdf (accessed 10 April, 2020).
ATSDR (2005). Agency for Toxic Substances and
Disease Registry. Toxicological profile for
nickel. Atlanta, GA: U.S. Department of
Health and Human Services, Public Health
Service.
https://www.atsdr.cdc.gov/toxprofiles/tp15.pd
f (accessed 10 April, 2020).
ATSDR (1999). Agency for Toxic Substances
and Disease Registry. Toxicological Profile
for
cadmium. US Department of Human and
Health Services.
ATSDR (2007). Agency for Toxic Substances and
Disease Registry. Toxicological profile for
arsenic. Draft for Public Comment.
ATSDR (2008). Agency for Toxic Substances
and Disease Registry. U.S. Department of
Health and human Services. Division of
Toxicology and Environmental Medicine and
Educational Services, Case Studies in
Environmental Medicine (CSEM) Cadmium
Toxicity Pp 20 -21. Available online:
https://www.atsdr.cdc.gov/csem/cadmium/do
cs/cadmium.pdf (accessed 14 April 2020).
ATSDR (2012). Agency for Toxic Substances and
Disease Registry. Toxicological profile for
chromium. Atlanta, GA: U.S. Department of
Health and Human Services, Public Health
Service.
https://www.atsdr.cdc.gov/toxprofiles/tp7.pdf (accessed 12 April 2020)
ATSDR (2004). Agency for Toxic Substances and
Disease Registry, U.S. Department of Health
and Human Services, Atlanta, GA.
Toxicological profile for copper.
Chaudhari, P. R., Tamrakar, N., Singh, L.,
Tandon, A. & Sharma, D. (2018). Rice
nutritional and medicinal properties: A review
article. Journal of Pharmacognosy and
Phytochemistry, 7, 2, pp. 150-156.
Chen, H., Yang, X., Wang, P., Wang, Z., Li, M. &
Zhao, F. (2018).Dietray cadmium intake from
rice and vegetables and potential health risk: A
case study in Xiangtan, Southern China.
Science of the Total Environment, 639, 15,
-277.
Chi, Y., Li, P., Tam, N. F., Liu, C., Ouyang, Y.,
Qi, X., Li, W, C. & Ye, Z. (2018). Variation in
grain cadmium and arsenic concentrations and
screening for stable low-accumulating rice
cultivars from multienvironment trials.
Science of the Total Environment, 643, 1, pp.
-1324.
COMA (Committee on Medical Aspects of Food
Policy) 1991. Dietary reference values for food
energy and nutrients for the United Kingdom.
Department of Health Report. HMSO.
London. 41, 181- 182. HMSO. London.
Copper Reference Dose (RfD),
https://www.michigan.gov/documents/deq/de
q-rrd-chem-CopperDatasheet_527899_7.pdf
(accessed 10 April 2020).
Daldrup, T., Haarhoff, K. & Szathmary, S. G.
(1985). Toedliche nickel sulphate –
intoxication. Berichtezur Gerichlichen
Medizin, 41, pp. 141 – 144.
Das, K.K., Das, S.N. & Dhundasi, S.A. (2008).
Nickel, its adverse health effects & oxidative
stress. Indian J Med Res., 128, pp. 412-425.
Deng, Y., Wang, M., Tian, T., Lin, S., Xu, P.,
Zhou, L., Dai, C., Hao, Q., Wu, Y., Zhai, Z.,
Zhu, Y., Zhuang, G. & Dai, Z. (2019). The
effect of hexavalent chromium on the
incidence and mortality of human cancers: A
metal-analysis based on published
epidemiological cohort studies. Frontier
Oncology, https://doi.org/10.3389/fonc 2019
.00024. Eddy, N. O. & Ekop, A. S. (2005). Comparative
studies of the level of toxicant in the seeds of
Terminalia catappa (Indian almond) and
Coulaedulis (African walnut). CHEMCLASS
Journal 2, pp. 14-76.
Eddy, N. O. & Udoh, C. L. (2005). Proximate
evaluation of the nutritional value of some
soup thickeners. CHEMCLASS Journal, 2, pp.
-14.
ENHIS, 2007. European Environment and Health
Information System. Exposure of children t
chemical hazards in food. Fact sheet No.44
http://www.euro.who.int/__data/assets/pdf_
file/ 0003/97446/4.4.pdf?ua= (accessed 13
th April 2020).
Environmental Protection Division (EPD) of the
Georgia Department of Natural Resources,
Atlanta,
GA 30334, United States. Human Health and
Marine mammal Risk.
https://www.epd.gov.hk/eia/register
/report/eiareport/eia_1062005/eia_report/eng/
html/Annex/Annex%20C.htm (Accessed 5th
of April 2020).
EPA (1986). Environmental Protection Agency.
Health assessment document for nickel and
nickel compounds, Research Triangle Park,
NC: Office of Health and Environmental
Assessment, Environmental Criteria and
Assessment Office, EPA-600/8- 83-012F.
NTIS PB86-232212.
FAO Rice Publications. http://www.fao.org/-
economic/est/publications/rice-publication -
s/en/. (15th April, 2020).
FAO/WHO (1982). Evaluations of the joint
FAO/WHO Committee on food additives
(JECFA).
Twenty - six meeting of the joint FAO/WHO
Expert committee on food additives.
FAO/WHO (2011). Safety evaluation of certain
contaminant in food. WHO food additives
series: 63,
FAO JECFA Monographs 6, seventy – second
meeting of the joint FAO/WHO Expert
committee on food additives.
FAO/WHO (2017). Joint FAO/WHO Food
Standards Programme, 2017. CODEX
Committee on Contaminant in Foods, Eleventh Session, Rio de Janeiro, Brazil.
FAOSTAT. (2018). Food and Agriculture
Organisation of the United Nations. Crops. http://www.fao.org/faostat/en/#data/QC/visua
lize. Accessed 3rd April, 2020.
Fowler, B.A., Alexander, J. & Oskersson, A.
(2015). Toxic metals in food, in: Nordberg, G.F., Fowler, B.A and Nordberg, M. (Eds),
Handbook of the Toxicology of Metals.
Academic Press, Armsterdam, pp. 123 – 140.
Gerba, C.P. (2019). Risk assessment, in: Brusseau,
M.L., Pepper, I.L and Gerba, C.P. (Eds),
Environmental and Pollution Science. Elsevier
Inc, pp. 541 – 563.
Goodman, J. E., Prueitt, R.L.., Thakali, S. & Oller,
A.R. (2011). The nickel ion bioavailability
model of the carcinogenic potential of nickelcontaining substances in the lung. Critical
Review and Toxicology, 41, pp. 142–174.
IARC (1990). International Agency for Research
on Cancer. Chromium, nickel and welding,
IARC
Monographs on the Evaluation of carcinogenic
risks to humans, Vol 49, France.
IARC (1987). Summaries & evaluations: Arsenic
and arsenic compounds (Group 1). Lyon,
International Agency for Research on Cancer,
p. 100 (IARC Monographs on the Evaluation
of Carcinogenic Risks to Humans, Supplement
Innocent, M.C., Asomugha, L. A., Ukamaka, M.
N. & Aronu, M.E. (2016). Ultrasound
measured testicular volume in Nigerian adults:
Relationship of the three formulae with
heights, body weight, body surface area, and
body – mass index. International Journal of
Advanced Medical Research, 3, pp. 85 – 90.
Ivica, K. (2015). Effects of soil contamination on
the selection of remediation method, in:
Nediljka, G. (Ed). Hand Book of Research on
Advancements in Environmental Engineering.
IGI Global, Pennsylvania, p. 205.
JECFA (2000). Summary and conclusions of the
fifty-fifth meeting, Geneva, 6–15 June 2000.
Geneva, World Health Organization, Joint
FAO/WHO Expert Committee on Food
Additives.
JECFA (2010). Summary and conclusions of the
seventy-second meeting of the Joint
FAO/WHO Expert Committee on Food
Additives, Rome, 16–25 February 2010. Rome,
Food and Agriculture
Organization of the United Nations; Geneva,
World Health Organization (JECFA/72/SC)
Juliano, B. O., Paul, A. & Tuano, P.(2019). Gross
structure and composition of the rice grain. DOI: 10.1016/B978-0-12-811508-4.00002-2
Liu, J., Ma, Z., Wang, M. & Sun, W. X. (2013).
Genotype differences among rice cultivars in
lead accumulation and translocation and the
relation with grain Pb levels. Ecotoxicology
and Environmental Safety, 90, 1, pp. 35-40.
Mao, C., Song, Y., Chen, L., Ji, J., Li. J., Yuan,
X., Yang, Z., Ayoko, G. A., Frost, R. L. &
Theiss, F. (2019). Human health risks of heavy
metals in paddy rice based on transfer
characteristics of heavy metals from soil to
rice. Catena, 175, pp. 339-348.
Mcgregor, D. B., Baan, R. A. Partensky, C. Rice,
J. M. & Wilbourn, J. D. (2000). Evaluation of
the carcinogic risks to humans associated with
surgical implants and other foreign bodies. A
report of an IARC Monographs Programme
Meeting. European Journal of Cancer, 36, pp.
– 313.
Muthayya, S., Sugimoto, J. D., Montgomery, S. &
Maberly, G. F. (2014). An overview of global
rice production, supply, trade, and
consumption. Ann N Y. Academy of Science, 1324, pp. 7-14.
National Standard of the People’s Republic of
China, (2012)G.B 2762 – 2012, National Food
Safety Standard, maximum levels of
contaminants in food.
Nawaz, A., Khuoshid, K., Arif, M.S. & Kanjha,
A.M. (2006). Accumulation of heavy metals in
soil and rice plant (oryza sativa L.) irrigated
with industrial effluents. International Journal
of Agricultural Biology, 8, pp. 391 – 393.
Nayar, N. M. (2014). Origins and Phylogeny of
Rice, Academic press, Armsterdam. pp. 1 -14.
New York State Department of Health (2020).
Chromium III and VI (reference Dose).
https://www.dec.ny.gov/docs/remediation_
hudson_pdf/appendixa.pdf (Accessed 8 April .
Ogunlade, O., Adalumo, O.A. & Asafa, M.A.
(2015). Challenges of body mass index
classification: new criteria for young adult
Nigerians. Nigeria Journal of Health Science, 15, pp. 71 – 74.
Oko, A. O., Ubi, B. E., Efisue, A. A. & Dambaba,
N. (2012). Comparative Analysis of the
Chemical Nutrient Composition of Selected
Local and Newly Introduced Rice Varieties
Grown in Ebonyi State of Nigeria
International Journal of Agriculture and
Forestry, 2, 2, pp. 16-23.
Oller, A.R., Costa, M. & Oberdorster, G. (1997).
Carcinogenicity assessment of selected nickel
compounds. Toxicology and Applied
Pharmacology., 143,pp. 152 – 166.
Onyedum, S. ., Adefolalu, F.S., Muhammad,
H.L., Apeh, D.O., Agada, M.S. & Imiewanrin,
M.R. (2020). Occurrence of major mycotoxins
and their dietary exposure in North – Central
Nigeria staples, Scientific African, 7, e00188.
https://doi.org/ 10.1016/j.sciaf.2019.e00188
Rice, K. M., Walker, E.M., Wu, M., Gillette, C. &
Blough, E. R., (2014). Environmental mercury
and its toxic effects. Journal of Preventive
Medicine and Public Health, 47, pp. 74 – 83.
Rossman, T. (2007). Arsenic, in: Rom, W., &
Markowitz, S., (Eds), Environmental and
Occupational Medicine. Lippincott Williams
& Wilkins, Maryland, pp. 1006–1017.
Satpathy, D., Rededy, M.V. & Dhal, S.P. (2014).
Risk assessment of heavy metals
contamination in paddy soil, plants, and grains
(Oryza sativa L.) at the East Coast of India,
Journal of Biomedicine and Biotechnology, 3,
, pp. 545473. https://doi.org/ 10.1155/
/545473
Selkop, S.k. & Oller, A.R. (2003). Respiratory
cancer risks associated with low – level nickel
exposure: an integrated assessment based on
animal, epidemiological and mechanistic data.
Regul. Toxicol. Pharmacol., 37, pp. 173 – 190.
Shabbir, M.A., Anjum, F.M., Khan, M.R.,
Nadeem, M. & Saeed, M. (2013). Assessment
of heavy metals and aflatoxin levels in export
quality Indica rice cultivars with different
milling fractions. African Journal of
Agricuktural Research, 8, pp. 3236 – 3244.
Simmons, R.W., Pongsakul, P., Saiyasit, P.D. &
Klinphoklap, S. (2005). Elevated levels of
cadmium and zinc in paddy soils and elevated
levels of cadmium in rice grain Downstream of
a zinc mineralized area in Thailand.
Implications for public health. Environmental
Geochemistry and Health, 27, pp. 501 – 511.
Simmons, R.W., Pongsakul, P., Chaney,
R.L., Saiyasitpanich, D. & Klinphoklap, S.W.
(2003). The relative exclusion of zinc and iron
from rice grain in relation to rice grain
cadmium as compared to soybean:
Implications for Human Health. Plant and
Soil, 257, pp. 163–170.
Sunderman, F.W., Dingle, B., Hopper, S.M. &
Swift, T. (1988). Acute nickel toxicity in
electroplating
workers who accidentally ingested a solution of
nickel sulphate and nickel chloride. Am. J.
Indust. Med., 14, pp. 257 – 266.
U.S. EPA (2000)Reference dose for methylmercury (External review draft,. U. S.
Environmental protection agency,
Washington, D.C., NCEA-S-0930.
United States Environmental Protection Agency
(US EPA) Arsenic, inorganic (reference
Dose). Environmental Protection Agency,
Integrated Risk Information Sstem;
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