Effect of Na-22, Cl-36, 3-H, and P-32 Exposure on Laboratory Clinical Researchers
Keywords:
Na-22, Cl-36, 3-H, P-32, occupational exposure, health workers, radioactive isotopes, radiological properties, protective measuresAbstract
Communication in Physical Sciences, 2023, 9(4): 438-446
Authors: Bertha Onyenachi Akagbue and Mu’awiya Baba Aminu
Received: 20 April 2023/Accepted 16 August 2023This research paper examines the potential health effects of occupational exposure to Na-22, Cl-36, 3-H, and P-32 isotopes on laboratory clinical researchers. The study aims to assess the risks associated with these radioactive isotopes commonly encountered in healthcare settings and provide insights into protective measures to mitigate these risks. Through a comprehensive literature review and analysis, the research paper discusses the radiological properties of these isotopes, exposure pathways, potential health risks, and best practices for ensuring the safety of laboratory and the health workers. The research study undertakes an in-depth exploration to evaluate the risks that healthcare professionals face while performing their duties, encompassing a range of medical applications from diagnostic procedures to advanced research endeavors. By amalgamating insights from an extensive literature review and meticulous analysis, this paper aspires to furnish a holistic understanding of the challenges and imperatives concerning the safeguarding of health workers engaged with these isotopes. The global literature has noted a notable rise in male infertility rates, prompting inquiries into its underlying factors. Some of this increase might be attributed to the impact of synthetic harmful substances, known as endocrine disruptors, on the endocrine system. Many of these substances are commonly used in various work settings. In this study, a comprehensive assessment of the specialized literature pertaining to the influence of occupational exposure to Na-22, Cl-36, and 3-H on the health of laboratory workers has been conducted, specifically with regard to their potential that causes infertility and etc
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References
Bennett, L. G. I., & Broberg, R. K. (2017). Labeling nucleic acids with radioactive phosphorus. In M. W. Pennington & C. C. Dickinson (Eds.), DNA Cloning and Assembly Methods (pp. 17-25). Humana Press.
Bergmann, H. H. & Sinzinger (1995). Radioactive Isotopes in Clinical Medicine and Research. Birkhäuser, Basel
Brown, M. S., & Langham, R. G. (2018). Chlorine-36: A radiotracer for Investigating Chloride Transport Mechanisms in Cells. Journal of Radioanalytical and Nuclear Chemistry, 318(, 2, pp. 983-992.
Carman, N. J. (2005). Endocrine-disrupting chemicals. http: //www.ghasp.org/publications/toxics_report/edc.htm (accessed in Feb/2005)
Creager, A. N. (2009) Phosphorus-32 in the Phage Group: radioisotopes as historical tracers of molecular biology. Stud Hist Philos Biol Biomed Sci., 40, 1, pp. 29-42. doi: 10.1016/j.shpsc.2008.12.005.
Cuttler, J. M. & Pollycove, M. (2017). Commentary: 3H-3He exchange in DNA and tritium in a lifetime. Dose-Response, 15, 3. 1559325817726665.
International Commission on Radiological Protection. (2020). Occupational radiological Protection in Interventional Procedures. ICRP Publication 139. Annals of the ICRP, 49(1_suppl), pp. 1-91.
Kathren, R. L. (1986). Radioactivity in the environment. Harwood Acad. Publ., New York.
Kavlock, R. J., Daston, G. P., De Rosa, C., Fenner-Crisp, P., Gray, L. E. & Kaattari, S, (1996). Research needs for the risk assessment of health and environmental effects of endocrine disruptors: a report of the U.S. EPA-sponsored workshop. Environ Health Perspect; 104, pp. 715-40.
Kron, J. V. (2007). An Introduction to Radiation Protection in Medicine. Institute of Physics Publishing, Bristol (2008), Taylor and Francis, London.
Martin J. E. (2000). Physics for Radiation protection. John Wiley & Sons, New York
Martin, C. J. (2003). Medical Imaging and radiation protection., John Wiley & Sons, New York
Melnick, R. L., (1999). Introduction – workshop on characterizing the effects of endocrine disruptors on human health at environmental exposure level. Environ Health Perspect; 107 Suppl 4:603-4.
Nelson, C. & Bunge, . R. (1974) Semen analysis: evidence for changing parameters of male fertility potential. Fertil Steril, 2, 5, pp. 503-507.
Queiroz, E. K. R. & Waissmann, W. (2006) Occupational Exposure and Male Reproductive System. Participated equally in the design, elaboration, formatting, and revision of the article. Cad. Saúde Pública, Rio de Janeiro, 22, 3, pp. :485-493.
Sanders, V. A. & Cutler, C. S. (2021). Radioarsenic: A promising theragnostic candidate for nuclear medicine. Nuclear Medicine and Biology, 92, pp. 184-201, https://doi.org/10.1016/j.nucmedbio.2020.03.004.
Santamarta J. (2001) Por um futuro sem contaminantes orgânicos persistentes. Agroecologia e Desenvolvimento Rural Sustentável, 2001, pp. 2:46-56.
Smith, A. M., Webb, W. L., McBride, T. M., & Siegel, S. B. (2015). The preparation and uses of Sodium 22. International Journal of Applied Radiation and Isotopes, 6, 3, pp. 192-197.
UN Scientific Committee on the effects of atomic radiation. (2018). Sources and effects of ionizing radiation. United Nations.
UNSCEAR. (2020). Report of the United Nations Scientific Committee on the effects of atomic radiation: Sixtieth session (p. 81). United Nations.
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