Antioxidant Properties and Reproductive Health Benefits of Opa eyin Herbal Concoction: In vitro and In vivo Evaluation
Keywords:
Opa eyin, Oxidative stress, Antioxidants, Reproductive healthAbstract
: There is an increased demand and consumption of aphrodisiac and reproductive-beneficial herbal mixtures in Nigeria. The empirical data to validate the perceived therapeutic properties of herbal concoctions like Opa eyin remains undocumented. Therefore, this study investigated the phytochemical composition and antioxidant properties of Opa eyin, a traditional herbal concoction used in South Western Nigeria. A total of 20 healthy male Wistar rats were assigned to 4 groups (n=5). The animals received graded doses of Opa in (0.20, 0.40, and 0.80 ml/kg body weight respectively) for 28 days. The animals were then sacrificed and the antioxidant evaluation of Opa eyin was carried out on the liver, kidney, and testes according to standard protocols. The data generated was subjected to statistical analysis in R statistical programming version 4.3.0. Phytochemical analysis revealed high levels of anthocyanins (109.91 mg/100 g), flavonoids (98.82 mg/100 g), steroids (58.39 mg/100 g), and alkaloids (56.55 mg/100 g), which are associated with antioxidant, anti-inflammatory, and antimicrobial effects. The concoction demonstrated significant (p < 0.05) in vitro antioxidant activity through DPPH radical scavenging, reducing power, and nitric oxide scavenging assays, exhibiting a dose-dependent response. In vivo experiments on Wistar rats revealed dose-dependent antioxidant effects in the liver, kidney, and testes. Opa eyin improved the reproductive health of the exposed animals, evidenced by reduced oxidative stress in the testes, suggesting potential benefits for fertility. These findings underscore its therapeutic potential and validate its traditional use, although further studies are needed to elucidate its long-term safety and efficacy.
Downloads
Published
Issue
Section
Similar Articles
- Chidumebi Uzoho, The Public Health Impact of Airborne Particulate Matter: Risks, Mechanisms, and Mitigation Strategies , Communication In Physical Sciences: Vol. 12 No. 2 (2025): VOLUME 12 ISSUE 2
- Idongesit Ignatius udo, A Comprehensive Review on Polymer Degradation: Mechanisms, Environmental Implications, and Sustainable Mitigation Strategies , Communication In Physical Sciences: Vol. 12 No. 3 (2025): VOLUME 12 ISSUE 3
- Umar Dangoje Musa, Eloayi David Paul, Sani Uba, Nsikan Nwokem, Sani Danladi, Risk Assessment of Selected Metallic Pollutants in Fish from Zuru dam, Kebbi State, Nigeria , Communication In Physical Sciences: Vol. 12 No. 3 (2025): VOLUME 12 ISSUE 3
- Bertha Onyenachi Akagbue Akagbue, Mu’awiya Baba Aminu , Effect of Na-22, Cl-36, 3-H, and P-32 Exposure on Laboratory Clinical Researchers , Communication In Physical Sciences: Vol. 9 No. 4 (2023): VOLUME 9 ISSUE 4
- Kingsley Ochommadu Kelechi , Onwubuariri Nnamdi Chukwuebuka, Chiazor Faustina Jisieike, Ezere, Uchechi Ahunna, Muyiwa Michael Orosun, Chisom Loveth Kelechi, Health Risk Assessment of Heavy Metal Contamination in Water Sources at Michael Okpara University of Agriculture , Communication In Physical Sciences: Vol. 12 No. 3 (2025): VOLUME 12 ISSUE 3
- Franca Amaka Nwafor, Augustine Friday Osondu Ador, Stress Concentration at a Sharp Corner of an Elastic Strip under Anti-Plane Strain , Communication In Physical Sciences: Vol. 11 No. 4 (2024): VOLUME 11 ISSUE 4
- Chidumebi Uzoho, The Role of Contaminated Water in Food Poisoning: An Assessment of Agricultural and Processing Practices , Communication In Physical Sciences: Vol. 12 No. 3 (2025): VOLUME 12 ISSUE 3
- Emeka Chima Ogoko, Aletan, Uduak Irene, Osu Charles Ikenna, Henrietta Ijeoma Kelle, Nnamdi Ibezim Ogoko, Heavy Metal Status and Health Risks Assessment of Some Local Alcoholic and Non-Alcoholic Beverages Consumed in Aba, Nigeria , Communication In Physical Sciences: Vol. 11 No. 4 (2024): VOLUME 11 ISSUE 4
- Olusegun Sawole, Kolawole Abiodun Egunjobi, Adebola Daniel Awofodu, Health Risk Assessment of Natural Radionuclides Ingestion from Selected Edible Crops in Farmlands Around Limestone Excavation Area in Ewekoro, Ogun State , Communication In Physical Sciences: Vol. 9 No. 4 (2023): VOLUME 9 ISSUE 4
- Faith Osaretin Osabuohien, Review of the Environmental Impact of Polymer Degradation , Communication In Physical Sciences: Vol. 2 No. 1 (2017): VOLUME 2 ISSUE 1
You may also start an advanced similarity search for this article.