Comparative Study of the Medicinal Values of Indigoferatinctoria and Gossypium Hirsutum
Keywords:
Indigoferatinctoria, Gossypium hirsutum, phytochemical and analysis,, antimicrobialAbstract
Communication in Physical Sciences, 2021, 7(4): 370-377
Authors: I. Ibrahim, A. Abdulazeez*, ,Z. M. Kolo, A. Usman, S. U. Nagenu, U. M. Badeggi, S. H. Mohammed,. A. I. Muhammad, and F. B. Salahuu
Received: 24 September 2021/Accepted 05 December 2021
Phytochemical screening was carried out using official and recommended analytical methods while the antimicrobial sensitivity test was implemented using the agar well diffusion method. From the phytochemical analysis of indigoferatinctoria extract, the results gotten, indicated the presence of significant concentrations of saponins, alkaloids and steroids, compared to the concentrations of flavonoids, tannins, glycoside, steroids(which were relatively minimal) and hydroxyl-anthraquinones (which was absent). The antimicrobial sensitive tests conducted on chloroform extract showed no activities against the selected bacteria, i.e Salmonella typhi, E.coli. Also, Staphylococcus aureus was not affected when treated with chloroform extract of Indigoferatinctoria but rather against ampicloxacillin control at 500 mg|ml The ethanolic extract showed minimal activities against E. coli and Staphylococcus aureus but not against Salmonella typhi Distilled water extract of indigoferatinctoria displayed activity against E.coli and Staphylococcus aureus but not against Salmonella typhi. Results recorded for phytochemical analysis indicated the presence of glycosides, alkaloids and steroids in all Gossypium hirsutum extract but not for tannins, flavanoid, and saponins extracts. The antimicrobial sensitivity test for antimicrobial of some selected organism against gossypiumhirutum extract shows no activities when treated with the plant extract in both ethanol and distilled water extract but shows minimum activity with chloroform extract against Salmonella typhi at 80mg/ml and 100mg/ml. From the results obtained,gossypiumhirsutum extract showed no activity against the pathogen The antimicrobial activity of Indigoferatinctoria and Gossypium hirsutum may be harnessed for the treatment of infections caused by bacteria if toxicological tests confirm gives negative results
Downloads
References
Adjeroh, L. A., Nwachukwu, M. O., Nnokwe, J. C., Azorji, J. N., Osinomumu, I. O. & Onyebuagu, P. C. (2020). Preliminary phytochemical screening and proximate analysis of Indigoferatinctoria L. (Uhe)Pod. Amazonian Journal of Plant Research, 4, pp. 3, pp. 639-645.
Amrithpal, .(2006). Medicinal plants of the world Oxford &IBH”.Publishing Co Pvt .Ltd New Delhi; 168.
AOAC, (2002) Association of Official Analytical analysis of International, 17thEdition. William AOAC, Association of analytical chemists.
Ashwini, ,S., Gajalakshmi, S., Mythili, A. & Sathiavelu, (2011). Terminalia chebula-A Pharmacological Review. Journal of Pharmacy Research, 4, 9, pp. 2884-2887.
Bakasso, S., Lamien, M., Lamien, C. E,. Keindrebeogo, M., Millogo, J.. Ouedraogo A. G. & Nacoulma, A.G. (2008). Polyphenol contents and antioxidant activities of five Indigoferaspecies (Fabaceae) from Burkina Faso, Pakistan Journal of Biological Sciences, .11, pp. 1435-1442.
Bisignano, G., Germano, M. P., Nostro, A. & Sanogo, R. (1996). Drugs used in Africa as dyes: antimicrobial activities. Phytotherapy Research, 9: pp. 346-350.
Carter, C .L. & Chesney, M. C. (1949). Hiptagenic acid identified as beta-nitropropionic acid, Nature, 164, pp. 575-576.
Culvenor, C.C.,. Foster, M. C. & Hegarty, M. P. (1971). A total synthesis of indospicine, 6-Amidino-2-aminohexanoic acid,. Australian Journal of Chemistry, .24, pp. 371-375.
Eisenbrand G., Hippe F., Jakobs S. & Muehlbeyer S. (2004). Molecular mechanisms of indirubin and its derivatives: novel anticancer molecules with their origin in traditional Chinese phytomedicine. Journal of Cancer Research and Clinical Oncology, 130, pp. 627-635.
Hartwell, J. L. (1967–1971). Plants used against cancer. A survey. Lloydia , pp. 30–34.
Kameswaran R & Ramanibhai R. (2008). Protective effect of flavonoids fraction of Indigoferatinctoria on Benzopyrene induced Lung carcinogenicity in Swiss Albino mice. International Journal of Cancer Research, 4, pp. 71-80.
List, P.H. & Horhammer, L. 1969–1979. Hager's handbuch der pharmazeutischen praxis. vols 2–6. Springer-Verlag, Berlin.
Martinez, C., Calero, A.,Dominguez ,X. A & Hinojosa, M.(1978). Louisfieserone, an unusual flavanone from Indigoferasuffruticosa, Tetrahedron Letters.5, pp. 429-432.
Mujeeb, F., Bajpai, P., & Pathak, N. (2014). Phytochemical Evaluation, Antimicrobial activity, and determination of bioactive components from leaves of Aeglemarmelos. BioMedica Research, http://doi.org/10.1 -155/2014/497606.
Muthulingam, M. Mohandoss, P. Indra, N. & Sethupathy, S.(2010).Antihepatotoxic efficacy of Indigoferatinctoria (Linn.) on paracetamol induced liver damage in rats. IJPBR;1(1):13-18
Nadkarni KM. (2005). Indian Plants and Drugs. New Delhi: Srishti Book Distributors; pp.172-3.
Narender, T., Khaliq, T., Puri ,A. & Chander, R. (2006). Antidyslipidemic activity of furano-flavonoids isolated from Indigoferatinctoria, Bioinorganic and Medicainal Chemistry, .16, pp. 3411-3414.
Seelanan, T., Schnabel A & Wendel, J. F. (1997). Congruence and consensus in the cotton tribe (Malvaceae). Syst Bot.;22, 2, pp. 259–90.
Sharma, V. & Agarwal, A. (2015). Phytochemical and antioxidant assays of methanol and hydromethanol extracts of ariel parts of Indigofera tinctorial Linn. Indian Journal of Pharmaceutical Science, 77, 6, pp. 729-734.
Sheikh, N. Kumar, Y. Misra, A. K. and Pfoz, L. 2013. Phytochemical screening to validate the ethnobotanical importance of root tubers of Dioscorea species of Meghalaya, North East India. Journal of Medicinal Plants Studies, 1, pp. 62–69.
Sharma, V. & Agarwal, A. (2015). Phytochemical and antioxidant assays of methanol and hydromethanol extracts of ariel parts of Indigofera tinctorial Linn. Indian Journal of Pharmaceutical Science, 77, 6, pp. 729-734.
Srinivasan, S., Wankhar, W., Rathinasamy, S. &Rajan, R. (2015). Free radical scavenging potential and HPTLC analysis of Indigoferatinctorialinn (Fabaceae), Journal of Pharmaceutical Analysis, 6, 2, pp. 125-131. https://doi.org/10.1016/j.jpha.2015.04.003.
Subramaniam, S. and Ayarivan, P. (2014). Cytokine mediated immunomodulatory properties of kaempferol-5-O-β-Dglucopyranoside from methanol extract of aerial parts of IndigoferaaspalathoidesVahl ex DC Swarnalatha, AyarivanPuratchikody International Journal of Research in Pharmaceutical Sciences, 5, pp, 1-6.
Tukan, S. K., Takruri, H. R. and Al –Eisaw, D. M. (1998). The use of wild edible plants in the Jordanian diet. International Journal of Food Sciences and Nutrition 49, pp.225 -235.
Verma S M, Suresh KB and Verma Amit(2010). Antidiabetic Activity of Leaves Indigoferatinctoria Linn (Fabaceae) International Journal of Toxicological and Pharmacological Research.:1, 2, pp. 42-43.
Verma, S. M. & Suresh, K. B. (2002). Phytochemical investigations of indigoferatinctorialinn leaves. Anc Sci Life., 21, 4, pp. 235-239
WarrierPK, NambiarVPK and C Ramankatty(2010). Indian medicinal plants. Published by Orient Longman Private Limited. Chenni, 3, pp. :210-213
Warrirer . P. K., Nambiar, V. P. K. & Ramankatty, C. (2007).Indian medicinal plants. Chennai: Orient Longman Private Limited, pp. 210-213.
Wendel, J. F., Brubaker, C. L.& Seelanan, T. (2010). .The origin and evolution of Gossypium. In: Stewart, J. M. et al., editors, Physiology of cotton. The Netherlands: Springer; pp.. 1–18.
Downloads
Published
Issue
Section
License
Copyright (c) 2021 The Journal and the author
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
